| Literature DB >> 31440743 |
Mohammad Aslam Khan1, Girijesh Kumar Patel1, Sanjeev Kumar Srivastava1,2, James Elliot Carter3, Jennifer Young Pierce4, Rodney Paul Rocconi4, Seema Singh1,5, Ajay Pratap Singh1,5.
Abstract
Cancer health disparities (CHDs), defined as the adverse differences in cancer incidence and mortality, are prevalent in certain racial and ethnic groups. Underlying causes of CHDs are multi-factorial and debatable. While low socioeconomic status, geographical location, lifestyle and behavioral factors are mostly believed to contribute to CHDs, regardless of ethnic and racial background, significant data now also exist to support a genetic basis of such disparities as well. Clearly, CHDs could best be understood by studying the interplay of multiple (genetic and non-genetic) factors and then translating the resulting knowledge into effective approaches for reducing the existing disparity gaps. This review article highlights these aspects in brief and calls the people of different expertise to work together to make an impact and tackle the challenges associated with CHDs.Entities:
Keywords: Cancer; ancestry; epigenetics; genetics; health disparities; socioeconomic status
Year: 2019 PMID: 31440743 PMCID: PMC6705599 DOI: 10.9777/chd.2019.1004
Source DB: PubMed Journal: Cancer Health Disparities ISSN: 2573-9530