Literature DB >> 3144044

The elav gene product of Drosophila, required in neurons, has three RNP consensus motifs.

S Robinow1, A R Campos, K M Yao, K White.   

Abstract

A sequence of developmental events transforms neurons from their immature state to their mature, terminally differentiated state. The elav locus is one of the first examples of a gene that is expressed in neurons early during this developmental sequence. This gene has been shown to be required for the proper development of young neurons and for the maintenance of mature neurons. DNA sequence data presented in this report suggest that the elav gene product is an RNA binding protein, based on the presence of RNP (ribonucleoprotein) consensus sequences. This leads to the proposal that this protein is involved in the RNA metabolism of neurons.

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Year:  1988        PMID： 3144044     DOI： 10.1126/science.3144044

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  100 in total

1.  Embryonic lethal abnormal vision-like RNA-binding proteins regulate neurite outgrowth and tau expression in PC12 cells.

Authors:  G E Aranda-Abreu; L Behar; S Chung; H Furneaux; I Ginzburg
Journal:  J Neurosci       Date:  1999-08-15       Impact factor: 6.167

2.  HuR regulates p21 mRNA stabilization by UV light.

Authors:  W Wang; H Furneaux; H Cheng; M C Caldwell; D Hutter; Y Liu; N Holbrook; M Gorospe
Journal:  Mol Cell Biol       Date:  2000-02       Impact factor: 4.272

3.  The RNA-binding protein HuD is required for GAP-43 mRNA stability, GAP-43 gene expression, and PKC-dependent neurite outgrowth in PC12 cells.

Authors:  C D Mobarak; K D Anderson; M Morin; A Beckel-Mitchener; S L Rogers; H Furneaux; P King; N I Perrone-Bizzozero
Journal:  Mol Biol Cell       Date:  2000-09       Impact factor: 4.138

Review 4.  Cytoplasmic polyadenylation in development and beyond.

Authors:  J D Richter
Journal:  Microbiol Mol Biol Rev       Date:  1999-06       Impact factor: 11.056

5.  Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.

Authors:  Katsumi Kasashima; Eiji Sakashita; Kuniaki Saito; Hiroshi Sakamoto
Journal:  Nucleic Acids Res       Date:  2002-10-15       Impact factor: 16.971

6.  Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory.

Authors:  Alessia Pascale; Pavel A Gusev; Marialaura Amadio; Tania Dottorini; Stefano Govoni; Daniel L Alkon; Alessandro Quattrone
Journal:  Proc Natl Acad Sci U S A       Date:  2004-01-26       Impact factor: 11.205

Review 7.  Cytoplasmic RNA-binding proteins and the control of complex brain function.

Authors:  Jennifer C Darnell; Joel D Richter
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-08-01       Impact factor: 10.005

8.  Sera from some patients with antibody-associated paraneoplastic encephalomyelitis/sensory neuronopathy recognize the Ro-52K antigen.

Authors:  G Manley; E Wong; J Dalmau; K Elkon; J Posner; H Furneaux
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

9.  Calreticulin interacts with C/EBPalpha and C/EBPbeta mRNAs and represses translation of C/EBP proteins.

Authors:  Lubov T Timchenko; Polina Iakova; Alana L Welm; Z-J Cai; Nikolai A Timchenko
Journal:  Mol Cell Biol       Date:  2002-10       Impact factor: 4.272

10.  Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.

Authors:  T D Levine; F Gao; P H King; L G Andrews; J D Keene
Journal:  Mol Cell Biol       Date:  1993-06       Impact factor: 4.272
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