| Literature DB >> 31439414 |
Abstract
Infectious and sterile injuries cause the release of PAMPs and DAMPs. A study by Liu et al. (Nat. Immunol. 2019) reports that DAMP-induced sterile brain inflammation from stroke is associated with sympathetic nervous system activation, enhancing intestinal permeability, the release of microbiota-derived PAMPs, and inflammation. TREM1 is implicated as a potential target to treat stroke and DAMP- and PAMP-induced inflammation.Entities:
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Year: 2019 PMID： 31439414 DOI： 10.1016/j.it.2019.07.008
Source DB: PubMed Journal: Trends Immunol ISSN： 1471-4906 Impact factor: 16.687