Said Yousef1,2, Jesse Elliott3,4, Douglas Manuel5,6,7, Ian Colman3,8, Manny Papadimitropoulos9,10, Alomgir Hossain3,6, Nathalie Leclair11, George A Wells3,4. 1. School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada. sabde029@uottawa.ca. 2. Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada. sabde029@uottawa.ca. 3. School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada. 4. Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada. 5. Ottawa Hospital Research Institute, Ottawa, ON, Canada. 6. Institute for Clinical Evaluative Sciences, Ottawa and Toronto, ON, Canada. 7. Department of Family Medicine, University of Ottawa, Ottawa, ON, Canada. 8. Canadian Institutes of Health Research, Ottawa, ON, Canada. 9. Eli Lilly Canada Inc, Toronto, ON, Canada. 10. Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada. 11. Berkman Library, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Abstract
BACKGROUND: A growing body of literature indicates that, worldwide, immigrants experience health deterioration after their arrival into their adopted country, and moreover, they have lower vitamin D compared to the native-born population. We plan to review if the levels of vitamin D are comparable between different ethnic groups in different regions of the world with those of native-born populations and to identify the possible associations between vitamin D deficiency and disease status among immigrants. METHODS/ DESIGN: A systematic review and meta-analysis will be conducted following the methods of the Cochrane handbook for systematic reviews. A literature search was performed to identify studies on immigrants and vitamin D. The primary outcome is vitamin D levels, and the secondary outcome is any vitamin D deficiency-related disease. Study design and participant characteristics will be extracted, including ethnicity, country of birth and/or origin, and the host country. Descriptive and meta-analytic summaries of the outcomes will be derived. Distiller-SR and RevMan will be used respectively for data management and meta-analysis. DISCUSSION: This systematic review may partially help clarify vitamin D-related health deterioration in migrants; moreover, to develop a global guideline that specifies sub-populations, in which the evidence and vitamin D-related recommendations might differ from the overall immigrant population. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42018086729.
BACKGROUND: A growing body of literature indicates that, worldwide, immigrants experience health deterioration after their arrival into their adopted country, and moreover, they have lower vitamin D compared to the native-born population. We plan to review if the levels of vitamin D are comparable between different ethnic groups in different regions of the world with those of native-born populations and to identify the possible associations between vitamin Ddeficiency and disease status among immigrants. METHODS/ DESIGN: A systematic review and meta-analysis will be conducted following the methods of the Cochrane handbook for systematic reviews. A literature search was performed to identify studies on immigrants and vitamin D. The primary outcome is vitamin D levels, and the secondary outcome is any vitamin D deficiency-related disease. Study design and participant characteristics will be extracted, including ethnicity, country of birth and/or origin, and the host country. Descriptive and meta-analytic summaries of the outcomes will be derived. Distiller-SR and RevMan will be used respectively for data management and meta-analysis. DISCUSSION: This systematic review may partially help clarify vitamin D-related health deterioration in migrants; moreover, to develop a global guideline that specifies sub-populations, in which the evidence and vitamin D-related recommendations might differ from the overall immigrant population. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42018086729.
Entities:
Keywords:
Immigrants’ health deterioration; Meta-analysis; Systematic review; Vitamin D
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