Literature DB >> 314384

Aplastic anemia following infectious mononucleosis: possible immune etiology.

R K Shadduck, A Winkelstein, Z Zeigler, J Lichter, M Goldstein, M Michaels, B Rabin.   

Abstract

A 17-year-old female developed severe aplastic anemia following serologically proven infectious mononucleosis. In vitro studies, using the granulocyte colony forming technique, suggested that the aplasia may have resulted from an immune mechanism. The patient's marrow grew no granulocyte colonies and caused inhibition of colony formation when mixed with normal marrows. The patient recovered fully after therapy with antithymocyte globulin and marrow cultures showed disappearance of the inhibitory effect. These observations suggest that the severe aplasia may have resulted from an aberrant immune response which followed infection by EB virus.

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Year:  1979        PMID： 314384

Source DB:  PubMed          Journal:  Exp Hematol        ISSN： 0301-472X            Impact factor:   3.084


  10 in total

1.  Aplastic anemia complicating infectious mononucleosis.

Authors:  C A Sawka; J A Bessette; B Furie; J F Desforges
Journal:  CMAJ       Date:  1987-04-01       Impact factor: 8.262

2.  Bone marrow transplantation in Canada.

Authors:  N A Buskard
Journal:  Can Med Assoc J       Date:  1980-07-05       Impact factor: 8.262

3.  Virus-induced transient bone marrow aplasia: major role of interferon-alpha/beta during acute infection with the noncytopathic lymphocytic choriomeningitis virus.

Authors:  D Binder; J Fehr; H Hengartner; R M Zinkernagel
Journal:  J Exp Med       Date:  1997-02-03       Impact factor: 14.307

4.  Pancytopenia with mixed cryoglobulinemia: evidence for anti-percursor cell activity of cryoglobulin--effects of plasmapheresis.

Authors:  P A Ginder; D F Middendorf; N I Abdou
Journal:  J Clin Immunol       Date:  1982-01       Impact factor: 8.317

5.  Effect of different modes of dialysis on serum erythropoietin levels in pediatric patients. A report of the Southwest Pediatric Nephrology Study Group.

Authors:  B S Beckman; J W Brookins; R K Shadduck; K F Mangan; L J Deftos; J W Fisher
Journal:  Pediatr Nephrol       Date:  1988-10       Impact factor: 3.714

6.  Pathogenic and host range determinants of the feline aplastic anemia retrovirus.

Authors:  N Riedel; E A Hoover; R E Dornsife; J I Mullins
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

7.  Coxsackievirus B3 infects the bone marrow and diminishes the restorative capacity of erythroid and lymphoid progenitors.

Authors:  Nadine Althof; J Lindsay Whitton
Journal:  J Virol       Date:  2012-12-26       Impact factor: 5.103

8.  Characterization of a virus that causes transient aplastic crisis.

Authors:  N S Young; P P Mortimer; J G Moore; R K Humphries
Journal:  J Clin Invest       Date:  1984-01       Impact factor: 14.808

9.  Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus.

Authors:  D Binder; M F van den Broek; D Kägi; H Bluethmann; J Fehr; H Hengartner; R M Zinkernagel
Journal:  J Exp Med       Date:  1998-06-01       Impact factor: 14.307

Review 10.  Microbe-Induced Inflammatory Signals Triggering Acquired Bone Marrow Failure Syndromes.

Authors:  J Luis Espinoza; Ritesh Kotecha; Shinji Nakao
Journal:  Front Immunol       Date:  2017-02-24       Impact factor: 7.561
  10 in total

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