Literature DB >> 31437933

Provenance Solutions for Medical Research in Heterogeneous IT-Infrastructure: An Implementation Roadmap.

Marcel Parciak1, Christian Bauer1, Theresa Bender1, Robert Lodahl1, Björn Schreiweis2, Erik Tute3, Ulrich Sax1.   

Abstract

Research data generated in large projects raise challenges about not only data analytics but also data quality assessments and data governance. The provenance of a data set - that is the history of data sets - holds information relevant to technicians and non-technicians and is able to answer questions regarding data quality, transparency, and more. We propose an implementation roadmap to extract, store, and utilize provenance records in order to make provenance available to data analysts, research subjects, privacy officers, and machines (machine readability). Each aspect is tackled separately, resulting in the implementation of a provenance toolbox. We aim to do so within the context of HiGHmed, a research consortium established within the medical informatics initiative in Germany. In this testbed of federated IT-infrastructures, the toolbox shall assist each stakeholder in answering domain-specific and domain-agnostic questions regarding the provenance of data sets. This way, we will improve data re-use, transparency, and reproducibility.

Keywords:  Data Accuracy; Metadata; Reproducibility of Results; Research

Mesh:

Year:  2019        PMID: 31437933     DOI: 10.3233/SHTI190231

Source DB:  PubMed          Journal:  Stud Health Technol Inform        ISSN: 0926-9630


  2 in total

Review 1.  Review of Clinical Research Informatics.

Authors:  Anthony Solomonides
Journal:  Yearb Med Inform       Date:  2020-08-21

2.  Towards standardization guidelines for in silico approaches in personalized medicine.

Authors:  Søren Brunak; Catherine Bjerre Collin; Katharina Eva Ó Cathaoir; Martin Golebiewski; Marc Kirschner; Ingrid Kockum; Heike Moser; Dagmar Waltemath
Journal:  J Integr Bioinform       Date:  2020-07-24
  2 in total

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