| Literature DB >> 3143705 |
A Takahashi1, H Nakamura, D Ikeda, H Naganawa, T Kameyama, S Kurasawa, Y Okami, T Takeuchi, Y Iitaka.
Abstract
A new antitumor antibiotic thrazarine was soluble in water and positive to anisaldehyde-sulfuric acid and ninhydrin color reactions. The absolute structure of thrazarine was determined to be O-[3R)-2-diazo-3-hydroxybutyryl)-L-serine by acid hydrolysis, spectroscopic analysis and X-ray crystallographic analysis. Structurally, thrazarine was a new member of azaserine group antibiotics.Entities:
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Year: 1988 PMID： 3143705 DOI： 10.7164/antibiotics.41.1568
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649