Á López-Díaz1, J L Fernández-González2, I Lara1, B Crespo-Facorro3,4,5, M Ruiz-Veguilla3,4,5,6. 1. UGC Salud Mental, Hospital Universitario Virgen Macarena, Sevilla, Spain. 2. UGC Salud Mental, Hospital San Juan de la Cruz, Úbeda, Spain. 3. UGC Salud Mental, Hospital Universitario Virgen del Rocío, Sevilla, Spain. 4. Departamento de Psiquiatría, Universidad de Sevilla, Sevilla, Spain. 5. Centro de Investigación Biomédica en Red Salud Mental (CIBERSAM), Barcelona, Spain. 6. Instituto de Biomedicina de Sevilla (IBIS), Grupo Psicosis y Neurodesarrollo, Sevilla, Spain.
Abstract
OBJECTIVES: To examine the prospective temporal stability of acute and transient psychotic disorders (ATPDs) and analyze whether there are clinical, psychopathological, or sociodemographic characteristics that predict ATPD diagnostic stability. METHOD: We conducted a prospective, 2-year, observational study of patients presenting a first-episode ATPD. A multivariate logistic regression model was developed to identify independent variables associated with ATPD diagnostic stability. Well-established predictive factors of diagnostic stability, as well as all the psychopathological features included in the ICD-10 Diagnostic Criteria for Research (DCR) descriptions of ATPD, were analyzed. RESULTS: Sixty-eight patients with a first episode of ATPD completed the study with a diagnostic stability rate as high as 55.9% (n = 38) at the end of the follow-up period. Multivariate analysis revealed that diagnostic stability was independently significantly associated with the baseline presence of motility disturbances (OR = 6.86, 95% CI = 1.10-42.62; P = 0.039), the absence of hallucinations (OR = 5.75, 95% CI = 1.51-21.98; P = 0.010), and the absence of schizophrenic features (OR = 7.13, 95% CI = 1.38-36.90; P = 0.019). CONCLUSION: A symptom checklist assessing these psychopathological features would enable early identification of those subjects whose initial ATPD diagnosis will remain stable over time.
OBJECTIVES: To examine the prospective temporal stability of acute and transient psychotic disorders (ATPDs) and analyze whether there are clinical, psychopathological, or sociodemographic characteristics that predict ATPD diagnostic stability. METHOD: We conducted a prospective, 2-year, observational study of patients presenting a first-episode ATPD. A multivariate logistic regression model was developed to identify independent variables associated with ATPD diagnostic stability. Well-established predictive factors of diagnostic stability, as well as all the psychopathological features included in the ICD-10 Diagnostic Criteria for Research (DCR) descriptions of ATPD, were analyzed. RESULTS: Sixty-eight patients with a first episode of ATPD completed the study with a diagnostic stability rate as high as 55.9% (n = 38) at the end of the follow-up period. Multivariate analysis revealed that diagnostic stability was independently significantly associated with the baseline presence of motility disturbances (OR = 6.86, 95% CI = 1.10-42.62; P = 0.039), the absence of hallucinations (OR = 5.75, 95% CI = 1.51-21.98; P = 0.010), and the absence of schizophrenic features (OR = 7.13, 95% CI = 1.38-36.90; P = 0.019). CONCLUSION: A symptom checklist assessing these psychopathological features would enable early identification of those subjects whose initial ATPD diagnosis will remain stable over time.
Authors: María José Valdés-Florido; Álvaro López-Díaz; Fernanda Jazmín Palermo-Zeballos; Nathalia Garrido-Torres; Paula Álvarez-Gil; Iván Martínez-Molina; Victoria Eugenia Martín-Gil; Elena Ruiz-Ruiz; Macarena Mota-Molina; María Paz Algarín-Moriana; Antonio Hipólito Guzmán-Del Castillo; Ángela Ruiz-Arcos; Rafael Gómez-Coronado; Sara Galiano-Rus; Alfonso Rosa-Ruiz; Juan Luis Prados-Ojeda; Luis Gutierrez-Rojas; Benedicto Crespo-Facorro; Miguel Ruiz-Veguilla Journal: Eur Arch Psychiatry Clin Neurosci Date: 2021-04-03 Impact factor: 5.270