Literature DB >> 31433963

Diabetes Impedes the Epigenetic Switch of Macrophages into Repair Mode.

Johanna A Knipper1, Xiaolei Ding2, Sabine A Eming3.   

Abstract

In this issue of Immunity, Kimball et al. (2019) show that restoring expression of the chromatin modifying enzyme Setdb2 in macrophages rescues impaired wound healing associated with type 2 diabetes. Their findings reveal epigenetic regulation as central to the resolution of macrophage-mediated inflammation in tissue repair and have therapeutic implications for the treatment of diabetic wounds.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID： 31433963     DOI： 10.1016/j.immuni.2019.07.009

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  6 in total

1.  Alternative polarization of resident macrophages improves hyperglycemia-associated male infertility.

Authors:  Xiaobin Zhu; Zhihong Niu; Weimin Fan; Meiyu Cheng; Qian Chen; Aijun Zhang
Journal:  iScience       Date:  2022-05-18

2.  Immune and repair responses in joint tissues and lymph nodes after knee arthroplasty surgery in mice.

Authors:  Yunwei Xia; Upneet K Sokhi; Richard D Bell; Tania Pannellini; Kathleen Turajane; Yingzhen Niu; Laura Frye; Max Chao; Ugur Ayturk; Miguel Otero; Mathias Bostrom; David Oliver; Xu Yang; Lionel B Ivashkiv
Journal:  J Bone Miner Res       Date:  2021-06-20       Impact factor: 6.390

Review 3.  The Emerging Role of Immune Cells and Targeted Therapeutic Strategies in Diabetic Wounds Healing.

Authors:  Jianying Song; Lixin Hu; Bo Liu; Nan Jiang; Houqiang Huang; JieSi Luo; Long Wang; Jing Zeng; Feihong Huang; Min Huang; Luyao Cai; Lingyu Tang; Shunli Chen; Yinyi Chen; Anguo Wu; Silin Zheng; Qi Chen
Journal:  J Inflamm Res       Date:  2022-07-20

4.  Distinct Inflammatory Macrophage Populations Sequentially Infiltrate Bone-to-Tendon Interface Tissue After Anterior Cruciate Ligament (ACL) Reconstruction Surgery in Mice.

Authors:  Takayuki Fujii; Susumu Wada; Camila B Carballo; Richard D Bell; Wataru Morita; Yusuke Nakagawa; Yake Liu; Daoyun Chen; Tania Pannellini; Upneet K Sokhi; Xiang-Hua Deng; Kyung Hyung Park-Min; Scott A Rodeo; Lionel B Ivashkiv
Journal:  JBMR Plus       Date:  2022-05-31

5.  Fasting before or after wound injury accelerates wound healing through the activation of pro-angiogenic SMOC1 and SCG2.

Authors:  Ming-Jie Luo; Shan-Shan Rao; Yi-Juan Tan; Hao Yin; Xiong-Ke Hu; Yan Zhang; Yi-Wei Liu; Tao Yue; Ling-Jiao Chen; Li Li; Ya-Rong Huang; Yu-Xuan Qian; Zheng-Zhao Liu; Jia Cao; Zhen-Xing Wang; Zhong-Wei Luo; Yi-Yi Wang; Kun Xia; Si-Yuan Tang; Chun-Yuan Chen; Hui Xie
Journal:  Theranostics       Date:  2020-02-19       Impact factor: 11.556

6.  MiR-144-5p, an exosomal miRNA from bone marrow-derived macrophage in type 2 diabetes, impairs bone fracture healing via targeting Smad1.

Authors:  Dong Zhang; Yifan Wu; Zonghuan Li; Hairen Chen; Siyuan Huang; Chao Jian; Aixi Yu
Journal:  J Nanobiotechnology       Date:  2021-07-30       Impact factor: 10.435
  6 in total

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