Literature DB >> 314335

High-dose methotrexate in malignant melanoma.

C P Karakousis, M Carlson.   

Abstract

High-dose methotrexate was given to 28 patients with advanced malignant melanoma who had previously failed to respond to two chemotherapy protocols. There were five instances of serious, but not fatal, toxicity. One patient has had an objective response and seven patients have had stabilization of disease with an average duration of 4 months.

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Year:  1979        PMID: 314335

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN: 0361-5960


  1 in total

1.  Paradoxical response of malignant melanoma to methotrexate in vivo and in vitro.

Authors:  J Gaukroger; L Wilson; M Stewart; Y Farid; T Habeshaw; N Harding; R Mackie
Journal:  Br J Cancer       Date:  1983-05       Impact factor: 7.640

  1 in total

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