OBJECTIVE: To evaluate the impact of Healthcare-Associated Infections on the hospitalization cost of children. METHOD: A prospective, quantitative cohort study involving children admitted to the Inpatient and Pediatric Intensive Care Units of a public university hospital. The data were analyzed through SPSS software by frequency distribution, central tendency measures and dispersion. The level of statistical significance was set at p<0.05 for all analyzes. RESULTS: The sample consisted of 173 children, of whom 18.5% developed Healthcare-Associated Infections, which increased the hospitalization costs 4.2 times (p<0.001). A greater cost impact was observed among patients with two or more infectious sites (R$81,037.57; p=0.010) and sepsis (R$46,315.63; p<0.001). Children colonized by multiresistant microorganisms with a prevalence of E. coli and A. baumannii ESBL also generated higher costs of R$35,206.15 and R$30,692.52, respectively. CONCLUSION: Healthcare-Associated Infections significantly increased the hospitalization costs for children, especially among those with more than two infectious sites, who developed sepsis or were colonized by multiresistant microorganisms.
OBJECTIVE: To evaluate the impact of Healthcare-Associated Infections on the hospitalization cost of children. METHOD: A prospective, quantitative cohort study involving children admitted to the Inpatient and Pediatric Intensive Care Units of a public university hospital. The data were analyzed through SPSS software by frequency distribution, central tendency measures and dispersion. The level of statistical significance was set at p<0.05 for all analyzes. RESULTS: The sample consisted of 173 children, of whom 18.5% developed Healthcare-Associated Infections, which increased the hospitalization costs 4.2 times (p<0.001). A greater cost impact was observed among patients with two or more infectious sites (R$81,037.57; p=0.010) and sepsis (R$46,315.63; p<0.001). Children colonized by multiresistant microorganisms with a prevalence of E. coli and A. baumannii ESBL also generated higher costs of R$35,206.15 and R$30,692.52, respectively. CONCLUSION: Healthcare-Associated Infections significantly increased the hospitalization costs for children, especially among those with more than two infectious sites, who developed sepsis or were colonized by multiresistant microorganisms.
Authors: Michelli Christina Magalhães Novais; Deusiane Santos Victor; Danielle da Silva Rodrigues; Bruno Oliveira Freitas; Nilo Manoel Pereira Vieira Barreto; Daiana de Jesus da Silva Mendes; Micheli Bernardone Saquetto Journal: Rev Paul Pediatr Date: 2021-06-23
Authors: Enrique Hernandez-Alonso; Nadège Bourgeois-Nicolaos; Margaux Lepainteur; Véronique Derouin; Simon Barreault; Adam Waalkes; Luis A Augusto; Stuti Gera; Orane Gleizes; Pierre Tissieres; Stephen J Salipante; Daniele de Luca; Florence Doucet-Populaire Journal: Microbiol Spectr Date: 2022-06-15