Literature DB >> 3142889

SPECT measurements with 99mTc-HM-PAO in focal epilepsy.

E Ryding1, I Rosén, D Elmqvist, D H Ingvar.   

Abstract

The ability of SPECT measurements with [99mTc]-HM-PAO (Ceretec) to find the location of the epileptic focus was studied in patients under consideration for neurosurgical treatment for therapy-resistant focal epilepsy. The location of low [99mTc]-HM-PAO uptake regions found at interictal measurements, and of high [99mTc]-HM-PAO uptake regions found at ictal measurements, was compared to the findings of extensive ictal and interictal EEG examinations, and to the results of CT and MRT. While EEG revealed focal epileptic activity in all of the 14 patients, SPECT showed regional abnormalities in 13 (93%). CT and MRT showed abnormal findings in 30%.

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Year:  1988        PMID: 3142889     DOI: 10.1038/jcbfm.1988.38

Source DB:  PubMed          Journal:  J Cereb Blood Flow Metab        ISSN: 0271-678X            Impact factor:   6.200


  2 in total

1.  Regional distribution of interictal 31P metabolic changes in patients with temporal lobe epilepsy.

Authors:  J van der Grond; J R Gerson; K D Laxer; J W Hugg; G B Matson; M W Weiner
Journal:  Epilepsia       Date:  1998-05       Impact factor: 5.864

2.  Limited value of interictal brain perfusion SPECT for detection of epileptic foci: high resolution SPECT studies in comparison with FDG-PET.

Authors:  T Nagata; F Tanaka; Y Yonekura; A Ikeda; S Nishizawa; K Ishizu; H Okazawa; K Terada; N Mikuni; I Yamamoto
Journal:  Ann Nucl Med       Date:  1995-05       Impact factor: 2.668

  2 in total

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