Literature DB >> 3142841

Glidobactins A, B and C, new antitumor antibiotics. II. Structure elucidation.

M Oka1, K Yaginuma, K Numata, M Konishi, T Oki, H Kawaguchi.   

Abstract

The structures of new antitumor antibiotics, glidobactins A (Ia), B (Ib) and C (Ic) were elucidated by a combination of chemical and enzymatic degradations and spectral analyses. They have in common a cyclized tripeptide nucleus composed of L-threonine, 4(S)-amino-2(E)-pentenoic acid and erythro-4-hydroxy-L-lysine, and differ from each other in the unsaturated fatty acid moiety attached to the peptide.

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Year:  1988        PMID： 3142841     DOI： 10.7164/antibiotics.41.1338

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  10 in total

1.  Improvement of glidobactin A production by Polyangium brachysporum.

Authors:  J A Titus; C A Roundy
Journal:  J Ind Microbiol       Date:  1990-11

2.  Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting.

Authors:  Jun Fu; Xiaoying Bian; Shengbaio Hu; Hailong Wang; Fan Huang; Philipp M Seibert; Alberto Plaza; Liqiu Xia; Rolf Müller; A Francis Stewart; Youming Zhang
Journal:  Nat Biotechnol       Date:  2012-05       Impact factor: 54.908

Review 3.  Proteasome inhibitors: an expanding army attacking a unique target.

Authors:  Alexei F Kisselev; Wouter A van der Linden; Herman S Overkleeft
Journal:  Chem Biol       Date:  2012-01-27

4.  Syrbactin proteasome inhibitor TIR-199 overcomes bortezomib chemoresistance and inhibits multiple myeloma tumor growth in vivo.

Authors:  Marquicia R Pierce; Reeder M Robinson; Tannya R Ibarra-Rivera; Michael C Pirrung; Nathan G Dolloff; André S Bachmann
Journal:  Leuk Res       Date:  2019-11-12       Impact factor: 3.156

5.  Production of cytotoxic glidobactins/luminmycins by Photorhabdus asymbiotica in liquid media and live crickets.

Authors:  Christine M Theodore; Jarrod B King; Jianlan You; Robert H Cichewicz
Journal:  J Nat Prod       Date:  2012-10-24       Impact factor: 4.050

6.  Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I.

Authors:  Alexander Amatuni; Anton Shuster; Alexander Adibekian; Hans Renata
Journal:  Cell Chem Biol       Date:  2020-08-06       Impact factor: 8.116

7.  Production of proteasome inhibitor syringolin A by the endophyte Rhizobium sp. strain AP16.

Authors:  Alexey Dudnik; Laurent Bigler; Robert Dudler
Journal:  Appl Environ Microbiol       Date:  2014-04-11       Impact factor: 4.792

8.  Natural product scaffolds as inspiration for the design and synthesis of 20S human proteasome inhibitors.

Authors:  Grace E Hubbell; Jetze J Tepe
Journal:  RSC Chem Biol       Date:  2020-09-16

9.  Room temperature electrocompetent bacterial cells improve DNA transformation and recombineering efficiency.

Authors:  Qiang Tu; Jia Yin; Jun Fu; Jennifer Herrmann; Yuezhong Li; Yulong Yin; A Francis Stewart; Rolf Müller; Youming Zhang
Journal:  Sci Rep       Date:  2016-04-20       Impact factor: 4.379

10.  Activation, Structure, Biosynthesis and Bioactivity of Glidobactin-like Proteasome Inhibitors from Photorhabdus laumondii.

Authors:  Lei Zhao; Camille Le Chapelain; Alexander O Brachmann; Marcel Kaiser; Michael Groll; Helge B Bode
Journal:  Chembiochem       Date:  2021-03-03       Impact factor: 3.164
  10 in total

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