Literature DB >> 31425933

Recent advances in deriving human endodermal tissues from pluripotent stem cells.

Daniel O Kechele1, James M Wells2.   

Abstract

The utilization of directed differentiation of human pluripotent stem cells to generate human tissues is quickly evolving. Here we review recent advances in the derivation and applications of human endodermal tissues, including the esophagus, lung, pancreas, liver, stomach, small intestine, and colon. Improvements in tissue transcriptional and functional maturation, multicellular complexity, and scalability allow better development and disease modeling, large-scale drug and toxicity screening, and potentially cell therapeutic applications.
Copyright © 2019 Elsevier Ltd. All rights reserved.

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Year:  2019        PMID： 31425933     DOI： 10.1016/j.ceb.2019.07.009

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  9 in total

Review 1.  Exploiting unique features of the gut-brain interface to combat gastrointestinal cancer.

Authors:  Alyssa Schledwitz; Guofeng Xie; Jean-Pierre Raufman
Journal:  J Clin Invest       Date:  2021-05-17       Impact factor: 14.808

Review 2.  Developmental basis of trachea-esophageal birth defects.

Authors:  Nicole A Edwards; Vered Shacham-Silverberg; Leelah Weitz; Paul S Kingma; Yufeng Shen; James M Wells; Wendy K Chung; Aaron M Zorn
Journal:  Dev Biol       Date:  2021-05-21       Impact factor: 3.582

Review 3.  Biomedical and societal impacts of in vitro embryo models of mammalian development.

Authors:  Naomi Moris; Cantas Alev; Martin Pera; Alfonso Martinez Arias
Journal:  Stem Cell Reports       Date:  2021-05-11       Impact factor: 7.765

4.  Charting human development using a multi-endodermal organ atlas and organoid models.

Authors:  Qianhui Yu; Umut Kilik; Emily M Holloway; Yu-Hwai Tsai; Christoph Harmel; Angeline Wu; Joshua H Wu; Michael Czerwinski; Charlie J Childs; Zhisong He; Meghan M Capeling; Sha Huang; Ian A Glass; Peter D R Higgins; Barbara Treutlein; Jason R Spence; J Gray Camp
Journal:  Cell       Date:  2021-05-20       Impact factor: 41.582

5.  Generation of esophageal organoids and organotypic raft cultures from human pluripotent stem cells.

Authors:  Vered Shacham-Silverberg; James M Wells
Journal:  Methods Cell Biol       Date:  2020-05-13       Impact factor: 1.829

6.  Retinoic acid receptor γ activation promotes differentiation of human induced pluripotent stem cells into esophageal epithelium.

Authors:  Yasufumi Koterazawa; Michiyo Koyanagi-Aoi; Keiichiro Uehara; Yoshihiro Kakeji; Takashi Aoi
Journal:  J Gastroenterol       Date:  2020-06-16       Impact factor: 7.527

Review 7.  The Intestinal Epithelium - Fluid Fate and Rigid Structure From Crypt Bottom to Villus Tip.

Authors:  Vangelis Bonis; Carla Rossell; Helmuth Gehart
Journal:  Front Cell Dev Biol       Date:  2021-05-20

Review 8.  Research in a time of enteroids and organoids: how the human gut model has transformed the study of enteric bacterial pathogens.

Authors:  Sridevi Ranganathan; Emily M Smith; Jennifer D Foulke-Abel; Eileen M Barry
Journal:  Gut Microbes       Date:  2020-11-09

Review 9.  Using multi-organ culture systems to study Parkinson's disease.

Authors:  Orly Reiner; Tamar Sapir; Arpan Parichha
Journal:  Mol Psychiatry       Date:  2020-11-05       Impact factor: 13.437
  9 in total

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