Literature DB >> 31425104

Temporal Views of Flattened Mitral Valve Geometries.

Pepe Eulzer, Sandy Engelhardt, Nils Lichtenberg, Raffaele de Simone, Kai Lawonn.   

Abstract

The mitral valve, one of the four valves in the human heart, controls the bloodflow between the left atrium and ventricle and may suffer from various pathologies. Malfunctioning valves can be treated by reconstructive surgeries, which have to be carefully planned and evaluated. While current research focuses on the modeling and segmentation of the valve, we base our work on existing segmentations of patient-specific mitral valves, that are also time-resolved ( 3D+t) over the cardiac cycle. The interpretation of the data can be ambiguous, due to the complex surface of the valve and multiple time steps. We therefore propose a software prototype to analyze such 3D+t data, by extracting pathophysiological parameters and presenting them via dimensionally reduced visualizations. For this, we rely on an existing algorithm to unroll the convoluted valve surface towards a flattened 2D representation. In this paper, we show that the 3D+t data can be transferred to 3D or 2D representations in a way that allows the domain expert to faithfully grasp important aspects of the cardiac cycle. In this course, we not only consider common pathophysiological parameters, but also introduce new observations that are derived from landmarks within the segmentation model. Our analysis techniques were developed in collaboration with domain experts and a survey showed that the insights have the potential to support mitral valve diagnosis and the comparison of the pre- and post-operative condition of a patient.

Entities:  

Year:  2019        PMID: 31425104     DOI: 10.1109/TVCG.2019.2934337

Source DB:  PubMed          Journal:  IEEE Trans Vis Comput Graph        ISSN: 1077-2626            Impact factor:   4.579


  2 in total

1.  Numerical biomechanics modelling of indirect mitral annuloplasty treatments for functional mitral regurgitation.

Authors:  Lee Galili; Adi White Zeira; Gil Marom
Journal:  R Soc Open Sci       Date:  2022-01-12       Impact factor: 2.963

2.  Mitral valve flattening and parameter mapping for patient-specific valve diagnosis.

Authors:  Nils Lichtenberg; Pepe Eulzer; Gabriele Romano; Andreas Brčić; Matthias Karck; Kai Lawonn; Raffaele De Simone; Sandy Engelhardt
Journal:  Int J Comput Assist Radiol Surg       Date:  2020-01-18       Impact factor: 2.924

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.