Literature DB >> 31424268

Advanced Tailored Randomness: A Novel Approach for Improving the Efficacy of Biological Systems.

Yaron Ilan1.   

Abstract

Improving the function of biological systems represents a significant task in the fight to control health conditions and slow down the aging process. Applying the laws of physics to a biological system is difficult, due to the multiple parameters that must be considered at the cellular and whole-organ levels. The second law of thermodynamics states that entropy, a measure of randomness in an isolated system, increases over time. Based on this concept, randomness has been suggested as a means by which the efficacy of isolated biological systems may be improved. While classical and quantum physics uses different definitions of randomness and complexity, biological randomness is as an essential component of the intrinsic unpredictability of life. The manifestation of biological randomness may be different for different individuals, leading to differences in patient outcomes. In this work, an approach for enhancing the effectiveness of biological systems based on a novel concept of advanced tailored randomness in patient care is presented.

Entities:  

Keywords:  algorithm; biological systems efficacy; quantum physics; randomness

Mesh:

Year:  2019        PMID: 31424268     DOI: 10.1089/cmb.2019.0231

Source DB:  PubMed          Journal:  J Comput Biol        ISSN: 1066-5277            Impact factor:   1.479


  12 in total

1.  Microtubules as a potential platform for energy transfer in biological systems: a target for implementing individualized, dynamic variability patterns to improve organ function.

Authors:  Yaron Ilan
Journal:  Mol Cell Biochem       Date:  2022-07-13       Impact factor: 3.842

2.  Personalized inherent randomness of the immune system is manifested by an individualized response to immune triggers and immunomodulatory therapies: a novel platform for designing personalized immunotherapies.

Authors:  Madi El-Haj; Dimitri Kanovitch; Yaron Ilan
Journal:  Immunol Res       Date:  2019-10       Impact factor: 2.829

Review 3.  Introducing variability in targeting the microtubules: Review of current mechanisms and future directions in colchicine therapy.

Authors:  Esther Forkosh; Ariel Kenig; Yaron Ilan
Journal:  Pharmacol Res Perspect       Date:  2020-08

Review 4.  A Personalized Signature and Chronotherapy-Based Platform for Improving the Efficacy of Sepsis Treatment.

Authors:  Ariel Kenig; Yaron Ilan
Journal:  Front Physiol       Date:  2019-12-19       Impact factor: 4.566

5.  Improving Global Healthcare and Reducing Costs Using Second-Generation Artificial Intelligence-Based Digital Pills: A Market Disruptor.

Authors:  Yaron Ilan
Journal:  Int J Environ Res Public Health       Date:  2021-01-19       Impact factor: 3.390

Review 6.  Digital Medical Cannabis as Market Differentiator: Second-Generation Artificial Intelligence Systems to Improve Response.

Authors:  Yaron Ilan
Journal:  Front Med (Lausanne)       Date:  2022-01-24

Review 7.  A Subject-Tailored Variability-Based Platform for Overcoming the Plateau Effect in Sports Training: A Narrative Review.

Authors:  Ram Gelman; Marc Berg; Yaron Ilan
Journal:  Int J Environ Res Public Health       Date:  2022-02-02       Impact factor: 3.390

Review 8.  Digital Analgesic Comprising a Second-Generation Digital Health System: Increasing Effectiveness by Optimizing the Dosing and Minimizing Side Effects.

Authors:  Henny Azmanov; Areej Bayatra; Yaron Ilan
Journal:  J Pain Res       Date:  2022-04-13       Impact factor: 2.832

Review 9.  Order Through Disorder: The Characteristic Variability of Systems.

Authors:  Yaron Ilan
Journal:  Front Cell Dev Biol       Date:  2020-03-20

Review 10.  Introducing Patterns of Variability for Overcoming Compensatory Adaptation of the Immune System to Immunomodulatory Agents: A Novel Method for Improving Clinical Response to Anti-TNF Therapies.

Authors:  Tawfik Khoury; Yaron Ilan
Journal:  Front Immunol       Date:  2019-11-20       Impact factor: 7.561

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