Literature DB >> 31422040

Analysis of medication data of women with uterine fibroids based on data mining technology.

Jianyan Xuan1, Guangfei Deng2, Rui Liu1, Xiangdong Chen1, Yuhua Zheng3.   

Abstract

The purpose of this study was to analyze the characteristics of the diagnosis and treatment of female uterine fibroids based on data mining technology and the medication rule. Clinical literature related to the treatment of uterine fibroids by Chinese National Knowledge Infrastructure (CNKI) from 2004 to 2018 were searched, and the literature meeting the requirements were selected according to the inclusion criteria and exclusion criteria. The contents of the prescription were recorded into the database, and the results of drug frequency, common drugs and core rules, etc. were obtained by the rule analysis of the software, so as to analyze the medication rules of modern doctors in treating uterine fibroids. Through research and analysis, it showed that common clinical drugs include leuprorelin (GnRH-a), danazol (androgen), gestrinone (progestin), mifepristone (progesterone receptor antagonist), and some cases of combination therapy. Based on the analysis of the frequency of drug, treatment effect and adverse drug reactions, it was found that the clinical application of mifepristone in the treatment of uterine fibroids was relatively common, with significant drug effect and mild adverse reactions, which was worthy of clinical promotion and application. Therefore, the results of this study provide a new basis for the clinical and basic research of traditional Chinese medicine in the treatment of uterine fibroids, but it still needs the verification of expert interpretation, experimental research and other methods.
Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Danazol; Data mining; Medical treatment; Mifepristone; Uterine fibroids

Mesh:

Substances:

Year:  2019        PMID: 31422040     DOI: 10.1016/j.jiph.2019.07.017

Source DB:  PubMed          Journal:  J Infect Public Health        ISSN: 1876-0341            Impact factor:   3.718


  3 in total

1.  A prospective interventional study to evaluate the effects of medical therapy (Mifepristone 25 mg) on the management of uterine fibroids.

Authors:  Meeta Gupta; Narita Jamwal; Sumeet Sabharwal; Shalini Sobti
Journal:  J Family Med Prim Care       Date:  2020-07-30

2.  Online Shopping Brand Sales Based on IoT Big Data Processing.

Authors:  Menglin Zhang; Xiaoyu Ma
Journal:  Comput Intell Neurosci       Date:  2022-03-26

3.  Medication Regularity of Traditional Chinese Medicine in the Treatment of Aplastic Anemia Based on Data Mining.

Authors:  Nanxi Dong; Xujie Zhang; Dijiong Wu; Zhiping Hu; Wenbin Liu; Shu Deng; Baodong Ye
Journal:  Evid Based Complement Alternat Med       Date:  2022-08-25       Impact factor: 2.650

  3 in total

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