| Literature DB >> 31421643 |
Stefan Stojkovic1, Anne Yaël Nossent1, Paul Haller2, Bernhard Jäger2,3, Kris G Vargas2, Johann Wojta1,4,5, Kurt Huber2,3.
Abstract
Microribonucleic acids (miRs) are small, noncoding ribonucleic acids (RNAs), which play an important role in the regulation of platelet function and activity. Several studies proposed a mechanistic role of platelet-related miRs in the pathophysiology of coronary artery disease (CAD) and atherothrombosis. Circulating, platelet-related miRs have been proposed as diagnostic, prognostic, as well as treatment response biomarkers in CAD and acute coronary syndrome (ACS). In this review, we summarize recent studies on the role of platelet-related miRs in the regulation of platelet function and activity. Furthermore, we review the studies investigating the role of platelet-related miRs as biomarkers in patients with CAD and ACS. Georg Thieme Verlag KG Stuttgart · New York.Entities:
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Year: 2019 PMID： 31421643 DOI： 10.1055/s-0039-1693702
Source DB: PubMed Journal: Thromb Haemost ISSN： 0340-6245 Impact factor: 5.249