Literature DB >> 31421631

Application of glycosylation in targeted drug delivery.

Fang Chen1, Gangliang Huang2.   

Abstract

Sugar, as a carrier of human energy and an important bioinformatics molecule, plays a vital role in many important physiological processes, and can control the transmission of bioinformatics by specific recognition with biological molecules such as proteins. Herein, the mechanism of glycosylation-targeted drug delivery was described, various glycosylation methods were summarized, and the applications of glycosylation-targeted drug delivery in liver targeting, brain targeting and lung targeting were discussed. At the same time, the problems of glycosylation targeted drug delivery were suggested, and the application prospects of glycosylation targeting drug delivery were expected.
Copyright © 2019 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Application; Glycosylation; Mechanisms; Targeted drug delivery

Mesh:

Substances:

Year:  2019        PMID: 31421631     DOI: 10.1016/j.ejmech.2019.111612

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  3 in total

1.  Molecular docking-guided synthesis of NSAID-glucosamine bioconjugates and their evaluation as COX-1/COX-2 inhibitors with potentially reduced gastric toxicity.

Authors:  Rachel A Jones Lipinski; Yann Thillier; Christophe Morisseau; Christopher S Sebastiano; Brian C Smith; C Dennis Hall; Alan R Katritzky
Journal:  Chem Biol Drug Des       Date:  2021-05-28       Impact factor: 2.817

Review 2.  Glycosylated Nanoparticles for Cancer-Targeted Drug Delivery.

Authors:  Sergio Andrés Torres-Pérez; Cindy Estefani Torres-Pérez; Martha Pedraza-Escalona; Sonia Mayra Pérez-Tapia; Eva Ramón-Gallegos
Journal:  Front Oncol       Date:  2020-11-30       Impact factor: 6.244

Review 3.  GDP-Mannose 3,5-Epimerase: A View on Structure, Mechanism, and Industrial Potential.

Authors:  Koen Beerens; Ophelia Gevaert; Tom Desmet
Journal:  Front Mol Biosci       Date:  2022-01-11
  3 in total

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