Literature DB >> 31421427

Fluid dynamics approach to airway obstruction.

Norihiko Tsuboi1, Shotaro Matsumoto2, Nao Nishimura2, Satoshi Nakagawa2, Hisato Kobayashi2.   

Abstract

BACKGROUND: Fluid dynamics theory, which is a fundamental underlying concept applied to fluid management, has not been introduced to analyze the human respiratory system. We hypothesized that one of the potential mechanisms that promotes airflow limitation in patients with airway obstructive disease would be elucidated by using fluid dynamics theory.
METHODS: We calculated the values of pressure loss and static pressure change under virtual tracheal stenotic conditions using the fluid dynamics approach.
RESULTS: Under normal conditions, the absolute values of pressure loss and static pressure change are very low. However, once airway stenosis occurs, it is confirmed that they would be dramatically elevated.
CONCLUSIONS: The fluid dynamics approach to airway obstruction is very constructive. The treatment strategy for airway obstruction and the reasons for airflow limitation are well explained by using this approach.
Copyright © 2019 Elsevier Ltd. All rights reserved.

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Year:  2019        PMID: 31421427     DOI: 10.1016/j.mehy.2019.109341

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  2 in total

1.  The Ventilatory Strategy to Minimize Expiratory Flow Rate in Ventilated Patients with Chronic Obstructive Pulmonary Disease.

Authors:  Norihiko Tsuboi; Kaoru Tsuboi; Nobuyuki Nosaka; Nao Nishimura; Satoshi Nakagawa
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2021-02-12

2.  Airflow and Particle Transport Prediction through Stenosis Airways.

Authors:  Parth Singh; Vishnu Raghav; Vignesh Padhmashali; Gunther Paul; Mohammad S Islam; Suvash C Saha
Journal:  Int J Environ Res Public Health       Date:  2020-02-10       Impact factor: 3.390

  2 in total

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