| Literature DB >> 31421263 |
Vadim V Tarasov1, Andrey A Svistunov1, Vladimir N Chubarev1, Samira A Dostdar1, Alexander V Sokolov1, Anna Brzecka2, Olga Sukocheva3, Margarita E Neganova4, Sergey G Klochkov4, Siva G Somasundaram5, Cecil E Kirkland5, Gjumrakch Aliev6.
Abstract
To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail.Entities:
Keywords: Cancer; Exosomes; Extracellular vesicles; Nanodrug delivery; Vaccines
Mesh:
Substances:
Year: 2019 PMID: 31421263 DOI: 10.1016/j.semcancer.2019.08.017
Source DB: PubMed Journal: Semin Cancer Biol ISSN: 1044-579X Impact factor: 15.707