Literature DB >> 31420690

[Innovation in diagnostics-mobile technologies].

Emrah Düzel1,2, Jochen René Thyrian3,4, David Berron5,6,7.   

Abstract

BACKGROUND: Progressive cognitive deficits are the main clinical symptom of Alzheimer's disease; however, the precise recording of cognitive deficits and assessment of their progression pose major problems in patient care and early interventions.
OBJECTIVE: Which problems for care and early intervention result from the current practice of cognitive assessment of patients with memory problems and which opportunities arise from the use of mobile apps?
MATERIAL AND METHODS: Evaluation of current care structures, discussion of basic work, expert recommendations and current developments.
RESULTS: The current practice of the pencil and paper-based diagnostics of cognitive deficits, which is temporally and spatially bound to a clinical environment, constrains the feasibility, validity and reliability of cognitive assessment and the quantification of progression. This limits the meaningful use of further diagnostic measures, such as magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) analyses. Recent progress in mobile app-based technologies, illustrated here with the example of the neotiv app, can help to overcome these problems.
CONCLUSION: Mobile app-based technologies can help to improve the cognitive assessment of patients with the main symptom of memory complaints. They can reduce overuse and underuse of diagnostic and therapeutic pathways and enable a targeted and meaningful use of advanced diagnostics. In addition, they can structure risk-modifying preventive measures, identify iatrogenic impairment of cognition and in this respect also strengthen patient competence.

Entities:  

Keywords:  Alzheimer’s disease; Cognition; Mild cognitive impairment; Mobile apps; Neuropsychology

Mesh:

Year:  2019        PMID: 31420690     DOI: 10.1007/s00115-019-0773-8

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  31 in total

1.  Executive dysfunction in Alzheimer disease.

Authors:  Margaret M Swanberg; Rochelle E Tractenberg; Richard Mohs; Leon J Thal; Jeffrey L Cummings
Journal:  Arch Neurol       Date:  2004-04

2.  Scoring higher the second time around: meta-analyses of practice effects in neuropsychological assessment.

Authors:  Matthew Calamia; Kristian Markon; Daniel Tranel
Journal:  Clin Neuropsychol       Date:  2012-04-30       Impact factor: 3.535

3.  Visual search in Dementia with Lewy Bodies and Alzheimer's disease.

Authors:  Kelly M Landy; David P Salmon; J Vincent Filoteo; William C Heindel; Douglas Galasko; Joanne M Hamilton
Journal:  Cortex       Date:  2015-09-21       Impact factor: 4.027

4.  Validating the DemTect with 18-fluoro-2-deoxy-glucose positron emission tomography as a sensitive neuropsychological screening test for early alzheimer disease in patients of a memory clinic.

Authors:  Armin Scheurich; Matthias J Muller; Thomas Siessmeier; Peter Bartenstein; Lutz G Schmidt; Andreas Fellgiebel
Journal:  Dement Geriatr Cogn Disord       Date:  2005-09-12       Impact factor: 2.959

5.  Differentiating the frontal presentation of Alzheimer's disease with FDG-PET.

Authors:  Michael C Woodward; Christopher C Rowe; Gareth Jones; Victor L Villemagne; Tammie A Varos
Journal:  J Alzheimers Dis       Date:  2015       Impact factor: 4.472

6.  Comparison of Prefrontal Atrophy and Episodic Memory Performance in Dysexecutive Alzheimer's Disease and Behavioral-Variant Frontotemporal Dementia.

Authors:  Stephanie Wong; Maxime Bertoux; Greg Savage; John R Hodges; Olivier Piguet; Michael Hornberger
Journal:  J Alzheimers Dis       Date:  2016       Impact factor: 4.472

7.  Dysexecutive versus amnesic phenotypes of very mild Alzheimer's disease are associated with distinct clinical, genetic and cortical thinning characteristics.

Authors:  Bradford C Dickerson; David A Wolk
Journal:  J Neurol Neurosurg Psychiatry       Date:  2010-06-20       Impact factor: 10.154

Review 8.  The preclinical phase of the pathological process underlying sporadic Alzheimer's disease.

Authors:  Heiko Braak; Kelly Del Tredici
Journal:  Brain       Date:  2015-08-17       Impact factor: 13.501

9.  Dementia care and general physicians--a survey on prevalence, means, attitudes and recommendations.

Authors:  Jochen René Thyrian; Wolfgang Hoffmann
Journal:  Cent Eur J Public Health       Date:  2012-12       Impact factor: 1.163

10.  PET Imaging of Tau Deposition in the Aging Human Brain.

Authors:  Michael Schöll; Samuel N Lockhart; Daniel R Schonhaut; James P O'Neil; Mustafa Janabi; Rik Ossenkoppele; Suzanne L Baker; Jacob W Vogel; Jamie Faria; Henry D Schwimmer; Gil D Rabinovici; William J Jagust
Journal:  Neuron       Date:  2016-03-02       Impact factor: 17.173

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