Literature DB >> 3142020

Effect of gold salt treatment on the receptor binding activity of monocytes and macrophages isolated from rats with adjuvant arthritis.

D R Haynes1, I R Garrett, B Vernon-Roberts.   

Abstract

We investigated the effect of chrysotherapy on the Fc and complement receptor binding activity of peripheral blood (PB) monocytes and peritoneal (PE) macrophages isolated from normal rats and rats with adjuvant induced arthritis. The adjuvant induced severe disease in Dark Agouti (DA) rats and less marked disease in J. C. Lewis (JC) rats. Gold treatment reduced the disease in DA rats but exacerbated the disease in JC rats. PB monocytes generally exhibited increased receptor activity after adjuvant injection. Gold treatment resulted in a simultaneous reduction of the PB monocyte receptor activity and increased the PE macrophage receptor activity. This was considered to be due to a direct effect of gold, since the Fc receptor activity of PE macrophages increased after in vitro gold treatment.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3142020     DOI： 10.1007/bf00270454

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN： 0172-8172            Impact factor:   2.631


  30 in total

1.  SIMPLIFIED MYELOPEROXIDASE STAIN USING BENZIDINE DIHYDROCHLORIDE.

Authors:  L S KAPLOW
Journal:  Blood       Date:  1965-08       Impact factor: 22.113

2.  Effects of gold salts and prednisolone on inflammatory cells. II. Suppression of inflammation and phagocytosis in the rat.

Authors:  B Vernon-Roberts; J D Jessop; J Doré
Journal:  Ann Rheum Dis       Date:  1973-07       Impact factor: 19.103

3.  Gold determination in biological fluids by atomic absorption spectrophotometry: application to chrysotherapy in rheumatoid arthritis patients.

Authors:  A Lorber; R L Cohen; C C Chang; H E Anderson
Journal:  Arthritis Rheum       Date:  1968-04

4.  Electron-dense deposits following injection of gold sodium thiomalate and thiomalic acid.

Authors:  W L Norton; D C Lewis; M Ziff
Journal:  Arthritis Rheum       Date:  1968-06

Review 5.  Origin and kinetics of monocytes and macrophages.

Authors:  R van Furth
Journal:  Semin Hematol       Date:  1970-04       Impact factor: 3.851

6.  Collagenase production by human mononuclear cells in culture: inhibition by gold containing compounds and other antirheumatic agents.

Authors:  A Ohta; J S Louie; J Uitto
Journal:  Ann Rheum Dis       Date:  1986-12       Impact factor: 19.103

7.  Gold-induced changes in the morphology and functional capabilities of human monocytes.

Authors:  K Ugai; M Ziff; P E Lipsky
Journal:  Arthritis Rheum       Date:  1979-12

8.  Adjuvant arthritis in the rat. Distribution of fluorescent material after footpad injection of rhodamine-labelled tubercle bacilli.

Authors:  B Vernon-Roberts; S P Liyanage; H L Currey
Journal:  Ann Rheum Dis       Date:  1975-10       Impact factor: 19.103

9.  Inhibition of antigen- and mitogen-induced human lymphocyte proliferation by gold compounds.

Authors:  P E Lipsky; M Ziff
Journal:  J Clin Invest       Date:  1977-03       Impact factor: 14.808

10.  Methyl ester of N-formylmethionyl-leucyl-phenylalanine: chemotactic responses of human blood monocytes and inhibition of gold compounds.

Authors:  P P Ho; A L Young; G L Southard
Journal:  Arthritis Rheum       Date:  1978 Jan-Feb
View more
  8 in total

1.  Professor Barrie Vernon-Roberts, AO, MD, BSc, PhD, FRCPath, FRCPA, FAOrthA (Hon), FRS.SA.

Authors:  K D Rainsford; D R Haynes
Journal:  Inflammopharmacology       Date:  2013-07-04       Impact factor: 4.473

2.  Complete prevention of the clinical expression of adjuvant-induced arthritis in rats by cyclosporin-A and lobenzarit: the regulation of lymph node cell populations and cytokine production.

Authors:  D R Haynes; S J Gadd; M W Whitehouse; G Mayrhofer; B Vernon-Roberts
Journal:  Inflamm Res       Date:  1996-04       Impact factor: 4.575

3.  Metallothionein induction in freshly isolated rat hepatocytes.

Authors:  P Coyle; J C Philcox; A M Rofe
Journal:  Biol Trace Elem Res       Date:  1993-01       Impact factor: 3.738

4.  Changes in plasma zinc, copper, iron, and hepatic metallothionein in adjuvant-induced arthritis treated with cyclosporin.

Authors:  A M Rofe; J C Philcox; D R Haynes; M W Whitehouse; P Coyle
Journal:  Biol Trace Elem Res       Date:  1992-09       Impact factor: 3.738

5.  The prostaglandin E1 analogue, misoprostol, regulates inflammatory cytokines and immune functions in vitro like the natural prostaglandins E1, E2 and E3.

Authors:  D R Haynes; M W Whitehouse; B Vernon-Roberts
Journal:  Immunology       Date:  1992-06       Impact factor: 7.397

6.  Is aspirin a prodrug for antioxidant and cytokine-modulating oxymetabolites?

Authors:  D R Haynes; P F Wright; S J Gadd; M W Whitehouse; B Vernon-Roberts
Journal:  Agents Actions       Date:  1993-05

7.  Metallothionein induction in cultured rat hepatocytes by arthritic rat serum, activated macrophages, interleukin-6, interleukin-11 and leukaemia inhibitory factor.

Authors:  P Coyle; J C Philcox; A M Rofe
Journal:  Inflamm Res       Date:  1995-11       Impact factor: 4.575

8.  A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition.

Authors:  Andrea Ilari; Paola Baiocco; Luigi Messori; Annarita Fiorillo; Alberto Boffi; Marina Gramiccia; Trentina Di Muccio; Gianni Colotti
Journal:  Amino Acids       Date:  2011-08-11       Impact factor: 3.520
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.