Literature DB >> 31418341

Magnetic Iron Oxide Nanoparticle Labeling of Photoreceptor Precursors for Magnetic Resonance Imaging.

Dae Joong Ma1,2, Mi-Sun Lim3,4, Un Chul Park1,2, Jung-Bum Park2, So Yeon Ji3,4, Hyeong Gon Yu1,2,4.   

Abstract

IMPACT STATEMENT: This study describes the methods and results of superparamagnetic iron oxide nanoparticle (SPION) labeling and magnetic resonance imaging (MRI) tracking of human embryonic stem cell-derived photoreceptor precursors transplanted into the subretinal space of Royal College of Surgeons rats. SPION labeling and MRI tracking provide information about the biodistribution of transplanted photoreceptor precursors, which is necessary for improving the functional benefits of cell therapy for degenerative retinal diseases.

Entities:  

Keywords:  degenerative retinal diseases; human embryonic stem cell; magnetic resonance imaging; photoreceptor precursor; superparamagnetic iron oxide nanoparticles

Mesh:

Substances:

Year:  2019        PMID: 31418341     DOI: 10.1089/ten.TEC.2019.0136

Source DB:  PubMed          Journal:  Tissue Eng Part C Methods        ISSN: 1937-3384            Impact factor:   3.056


  2 in total

1.  Subretinal versus intravitreal administration of human CD34+ bone marrow-derived stem cells in a rat model of inherited retinal degeneration.

Authors:  Un Chul Park; Susanna S Park; Bo Hee Kim; Sung Wook Park; Young Joo Kim; Whitney Cary; Johnathon D Anderson; Jan A Nolta; Hyeong Gon Yu
Journal:  Ann Transl Med       Date:  2021-08

Review 2.  Nanoparticles in ocular applications and their potential toxicity.

Authors:  Cao Yang; Junling Yang; Ao Lu; Jing Gong; Yuanxing Yang; Xi Lin; Minghui Li; Haiwei Xu
Journal:  Front Mol Biosci       Date:  2022-07-15
  2 in total

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