| Literature DB >> 31418330 |
Masaaki Ito1, Taku Toriumi2, Hideto Imura1, Yasunori Akiyama1, Yoshinori Arai3, Nagato Natsume1, Masaki Honda2.
Abstract
IMPACT STATEMENT: The rat palatine fissure is anatomically similar to human alveolar cleft. In this study, we examined potential bone repair by an autologous bone implant and beta-tricalcium phosphate (β-TCP) using rat palatine fissure as a model. Autologous bone chips or β-TCP granules were implanted into the rat palatine fissure. Our model demonstrated that higher bone volume and bone mineral density were achieved with autologous bone graft than with β-TCP. We have provided the first demonstration of the suitability of the rat palatine fissure as the implant site to simulate the transplantation of bone graft materials into human alveolar cleft.Entities:
Keywords: bone graft materials; bone regeneration; congenital bone defect; human alveolar cleft; rat palatine fissure
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Year: 2019 PMID： 31418330 DOI： 10.1089/ten.TEC.2019.0143
Source DB: PubMed Journal: Tissue Eng Part C Methods ISSN： 1937-3384 Impact factor: 3.056