Sung-Yoon Kang1, Ha-Kyeong Won2, Sang Min Lee1, Jae-Woo Kwon3, Min-Hye Kim4, Eun-Jung Jo5, Seung-Eun Lee6, Sae-Hoon Kim7, Yoon-Seok Chang7, Sang Pyo Lee1, Byung-Jae Lee8, Sang-Heon Cho9, Surinder S Birring10, Woo-Jung Song11. 1. Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea. 2. Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. 3. Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea. 4. Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea. 5. Department of Internal Medicine, Pusan National University Hospital, Busan, Korea. 6. Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea. 7. Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. 8. Division of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. 9. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. 10. Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK. 11. Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. swj0126@amc.seoul.kr.
Abstract
PURPOSE: Chronic cough is a common problem in various populations. The present study assessed the impact of cough and unmet needs in Korean patients with chronic cough. METHODS: This cross-sectional multi-center study enrolled adult patients newly referred to clinic for assessment of chronic cough. A second group of patients with unexplained chronic cough following detailed assessment were recruited for comparison. Patients completed self-reported questionnaires, including cough characteristics, impact of cough on daily life, and unmet needs. RESULTS: A total of 447 subjects were recruited from six referral clinics, including 408 with chronic cough and 39 with unexplained chronic cough. Almost all patients reported that cough impacted their daily lives. Psychosocial impacts were more evident in unexplained cough patients compared to newly referred patients. Approximately 75% of newly referred patients had previously sought medical care for cough on multiple occasions, but the effectiveness of treatment was limited (70.3%) or absent (17.3%). The most frequent unmet need was the ineffectiveness of treatment (49.3%), followed by unclear diagnosis (30.1%). The majority of participants ( > 80%) expressed the need for further information on accessing cough specialists and disease management. The main problem faced by unexplained cough patients was poor cough control despite treatment (64%). CONCLUSIONS: Chronic cough has a substantial impact on daily life and is worst in those whose cough remains unexplained following assessment. Ineffectiveness of treatment and unclear diagnosis were major unmet needs. Medical information about chronic cough was also lacking. Improvements in the management of chronic cough patients in Korea are necessary.
PURPOSE:Chronic cough is a common problem in various populations. The present study assessed the impact of cough and unmet needs in Korean patients with chronic cough. METHODS: This cross-sectional multi-center study enrolled adult patients newly referred to clinic for assessment of chronic cough. A second group of patients with unexplained chronic cough following detailed assessment were recruited for comparison. Patients completed self-reported questionnaires, including cough characteristics, impact of cough on daily life, and unmet needs. RESULTS: A total of 447 subjects were recruited from six referral clinics, including 408 with chronic cough and 39 with unexplained chronic cough. Almost all patients reported that cough impacted their daily lives. Psychosocial impacts were more evident in unexplained coughpatients compared to newly referred patients. Approximately 75% of newly referred patients had previously sought medical care for cough on multiple occasions, but the effectiveness of treatment was limited (70.3%) or absent (17.3%). The most frequent unmet need was the ineffectiveness of treatment (49.3%), followed by unclear diagnosis (30.1%). The majority of participants ( > 80%) expressed the need for further information on accessing cough specialists and disease management. The main problem faced by unexplained coughpatients was poor cough control despite treatment (64%). CONCLUSIONS:Chronic cough has a substantial impact on daily life and is worst in those whose cough remains unexplained following assessment. Ineffectiveness of treatment and unclear diagnosis were major unmet needs. Medical information about chronic cough was also lacking. Improvements in the management of chronic coughpatients in Korea are necessary.
Entities:
Keywords:
Chronic cough; Quality of life; Questionnaire survey; Unmet needs
Authors: Sarah A F Chamberlain; Rachel Garrod; Abdel Douiri; Sarah Masefield; Pippa Powell; Catherine Bücher; Anand Pandyan; Alyn H Morice; Surinder S Birring Journal: Lung Date: 2015-03-19 Impact factor: 2.584
Authors: Alyn H Morice; Madhav S Menon; Siobhan A Mulrennan; Caroline F Everett; Caroline Wright; Jennifer Jackson; Rachel Thompson Journal: Am J Respir Crit Care Med Date: 2006-11-22 Impact factor: 21.405
Authors: Alyn H Morice; Eva Millqvist; Maria G Belvisi; Kristina Bieksiene; Surinder S Birring; Kian Fan Chung; Roberto W Dal Negro; Peter Dicpinigaitis; Ahmad Kantar; Lorcan P McGarvey; Adalberto Pacheco; Raimundas Sakalauskas; Jaclyn A Smith Journal: Eur Respir J Date: 2014-08-19 Impact factor: 16.671
Authors: Philip W Rouadi; Samar A Idriss; Jean Bousquet; Tanya M Laidlaw; Cecilio R Azar; Mona S Al-Ahmad; Anahi Yañez; Maryam Ali Y Al-Nesf; Talal M Nsouli; Sami L Bahna; Eliane Abou-Jaoude; Fares H Zaitoun; Usamah M Hadi; Peter W Hellings; Glenis K Scadding; Peter K Smith; Mario Morais-Almeida; René Maximiliano Gómez; Sandra N Gonzalez Diaz; Ludger Klimek; Georges S Juvelekian; Moussa A Riachy; Giorgio Walter Canonica; David Peden; Gary W K Wong; James Sublett; Jonathan A Bernstein; Lianglu Wang; Luciana K Tanno; Manana Chikhladze; Michael Levin; Yoon-Seok Chang; Bryan L Martin; Luis Caraballo; Adnan Custovic; Jose Antonio Ortega-Martell; Erika Jensen-Jarolim; Motohiro Ebisawa; Alessandro Fiocchi; Ignacio J Ansotegui Journal: World Allergy Organ J Date: 2021-11-22 Impact factor: 4.084
Authors: Ha Kyeong Won; Ji Hyang Lee; Jin An; Kyoung Hee Sohn; Min Gyu Kang; Sung Yoon Kang; Alyn H Morice; Sang Heon Cho; Woo Jung Song Journal: Allergy Asthma Immunol Res Date: 2020-11 Impact factor: 5.764
Authors: Allison Martin Nguyen; Elizabeth D Bacci; Margaret Vernon; Surinder S Birring; Carmen La Rosa; David Muccino; Jonathan Schelfhout Journal: Ther Adv Respir Dis Date: 2021 Jan-Dec Impact factor: 4.031