Literature DB >> 31417046

Demographic and clinical characteristics of keloids in an urban center in Sub-Sahara Africa.

O Belie1, A O Ugburo1, B O Mofikoya1.   

Abstract

BACKGROUND: Keloid is a major complication of wound healing. The clinical spectrum ranges from unaesthetic lesions minimally invading the adjacent skin to large grotesque lesions sometimes associated with contractures. SUBJECTS AND METHODS: The patients were seen over 2 years in a tertiary hospital setting. The following information was obtained with a proforma: the biodata, etiology of keloid, region affected, symptoms, and treatment prior to presentation. The keloids were examined and the sizes were grouped into small, medium, and large keloids; the severities of symptoms were determined using the visual analog scale.
RESULTS: 159 patients with 224 keloids were seen over 2-year period with male-to-female ratio of 1:1.24. The most common causes of keloid were trauma and acne (27.0% and 20.1%, respectively). The trunk had a statistically significant higher number of symptomatic keloid compared with other regions keloids. The larger keloids were more symptomatic compared with the smaller ones, P = 0.000. There were more pruritic keloids than painful ones. About 25% of patients had positive family history in first-degree relative, 16% in second-degree relative, and their keloid are more symptomatic than those without family history.
CONCLUSION: In view of the burden of keloids, early treatment is advised. Unnecessary trauma and extra piercing should be avoided; elective surgeries that are deferrable should be postponed until when necessary.

Entities:  

Keywords:  Keloid; pain; pruritus

Mesh:

Year:  2019        PMID: 31417046     DOI: 10.4103/njcp.njcp_395_18

Source DB:  PubMed          Journal:  Niger J Clin Pract            Impact factor:   0.968


  2 in total

1.  IL-4 and CCR7 play an important role in the development of keloids in patients with a family history.

Authors:  Mengjie Shan; Hao Liu; Yan Hao; Tian Meng; Cheng Feng; Kexin Song; Youbin Wang
Journal:  Am J Transl Res       Date:  2022-05-15       Impact factor: 3.940

2.  MicroRNA-21 may be involved in the therapeutic effects of Galla chinensis ointment on keloid.

Authors:  Zhiming Tang; Jicun Ding; Xiaoxiang Zhai; Mengqing Jing; Zhiqiang Guan; Yongcong Li
Journal:  J Int Med Res       Date:  2020-03       Impact factor: 1.671

  2 in total

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