Literature DB >> 31416539

Estimation of life expectancies using continuous-time multi-state models.

Ardo van den Hout1, Mei Sum Chan2, Fiona Matthews3.   

Abstract

BACKGROUND AND
OBJECTIVE: There is increasing interest in multi-state modelling of health-related stochastic processes. Given a fitted multi-state model with one death state, it is possible to estimate state-specific and marginal life expectancies. This paper introduces methods and new software for computing these expectancies.
METHODS: The definition of state-specific life expectancy given current age is an extension of mean survival in standard survival analysis. The computation involves the estimated parameters of a fitted multi-state model, and numerical integration. The new R package elect provides user-friendly functions to do the computation in the R software.
RESULTS: The estimation of life expectancies is explained and illustrated using the elect package. Functions are presented to explore the data, to estimate the life expectancies, and to present results.
CONCLUSIONS: State-specific life expectancies provide a communicable representation of health-related processes. The availability and explanation of the elect package will help researchers to compute life expectancies and to present their findings in an assessable way. Crown
Copyright © 2019. Published by Elsevier B.V. All rights reserved.

Keywords:  Gompertz distribution; Interval censoring; Markov model; Panel data; Sojourn time; Stochastic process

Mesh:

Year:  2019        PMID: 31416539     DOI: 10.1016/j.cmpb.2019.06.004

Source DB:  PubMed          Journal:  Comput Methods Programs Biomed        ISSN: 0169-2607            Impact factor:   5.428


  4 in total

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  4 in total

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