Literature DB >> 31416396

Skin immunity and its dysregulation in psoriasis.

Caterina Lanna1, Mara Mancini2, Roberta Gaziano3, Maria Vittoria Cannizzaro1, Marco Galluzzo1, Marina Talamonti1, Valentina Rovella2, Margherita Annicchiarico-Petruzzelli2, Gerry Melino2,3, Ying Wang4, Yufang Shi4,5, Elena Campione1, Luca Bianchi1.   

Abstract

The skin is a peripheral lymphoid organ, being the first immunological defense against infections as the initial interface between the organism and the external background. The maintenance of the skin immune homeostasis depends on a finely equilibrium of well-regulated relations between different cells and exogenous pathogens. Inflammatory skin diseases are directly linked to the dysregulation of this equilibrium. The present review discusses the role of the immune system, of T cells, in the etiopathogenesis of psoriasis, illustrating a potential rationale for innovative therapeutic intervention.

Entities:  

Keywords:  Psoriasis; biologic therapies; cytokines; immunity; lymphocytes

Mesh：

Substances：

Year:  2019        PMID： 31416396      PMCID： PMC6773242          DOI： 10.1080/15384101.2019.1653099

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  73 in total

1.  CD56brightCD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation.

Authors:  Chiara Ottaviani; Francesca Nasorri; Chiara Bedini; Ornella de Pità; Giampiero Girolomoni; Andrea Cavani
Journal:  Eur J Immunol       Date:  2006-01       Impact factor: 5.532

Review 2.  Skin microbiota: a source of disease or defence?

Authors:  A L Cogen; V Nizet; R L Gallo
Journal:  Br J Dermatol       Date:  2008-03       Impact factor: 9.302

3.  Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation.

Authors:  Yihua Cai; Xiaoyan Shen; Chuanlin Ding; Chunjian Qi; Kejia Li; Xia Li; Venkatakrishna R Jala; Huang-ge Zhang; Tian Wang; Jie Zheng; Jun Yan
Journal:  Immunity       Date:  2011-10-06       Impact factor: 31.745

Review 4.  Deconstructing networks of p53-mediated tumor suppression in vivo.

Authors:  Alyssa M Kaiser; Laura D Attardi
Journal:  Cell Death Differ       Date:  2017-11-03       Impact factor: 15.828

Review 5.  Cytokines and anticytokines in psoriasis.

Authors:  Aldona T Pietrzak; Anna Zalewska; Grazyna Chodorowska; Dorota Krasowska; Anna Michalak-Stoma; Piotr Nockowski; Paweł Osemlak; Tomasz Paszkowski; Jacek M Roliński
Journal:  Clin Chim Acta       Date:  2008-04-12       Impact factor: 3.786

6.  Novel isatin-derived molecules activate p53 via interference with Mdm2 to promote apoptosis.

Authors:  Olga Fedorova; Alexandra Daks; Varvara Petrova; Alexey Petukhov; Larissa Lezina; Oleg Shuvalov; Pavel Davidovich; Darya Kriger; Ekaterina Lomert; Dmitry Tentler; Victor Kartsev; Burhan Uyanik; Vyacheslav Tribulovich; Oleg Demidov; Gerry Melino; Nickolai A Barlev
Journal:  Cell Cycle       Date:  2018-09-05       Impact factor: 4.534

7.  p63 is upstream of IKK alpha in epidermal development.

Authors:  Eleonora Candi; Alessandro Terrinoni; Alessandro Rufini; Anissa Chikh; Anna Maria Lena; Yasuhiro Suzuki; Berna S Sayan; Richard A Knight; Gerry Melino
Journal:  J Cell Sci       Date:  2006-11-15       Impact factor: 5.285

Review 8.  More alive than dead: non-apoptotic roles for caspases in neuronal development, plasticity and disease.

Authors:  Amrita Mukherjee; Darren W Williams
Journal:  Cell Death Differ       Date:  2017-06-23       Impact factor: 15.828

9.  Involvement of IL-9 in Th17-associated inflammation and angiogenesis of psoriasis.

Authors:  Tej Pratap Singh; Michael P Schön; Katrin Wallbrecht; Alexandra Gruber-Wackernagel; Xiao-Jing Wang; Peter Wolf
Journal:  PLoS One       Date:  2013-01-15       Impact factor: 3.240

Review 10.  Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism.

Authors:  Alice Nemajerova; Ivano Amelio; Jakob Gebel; Volker Dötsch; Gerry Melino; Ute M Moll
Journal:  Cell Death Differ       Date:  2017-10-27       Impact factor: 15.828
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  5 in total

Review 1.  Update on the etiopathogenesis of psoriasis (Review).

Authors:  Daciana Elena Branisteanu; Catalina Cojocaru; Roxana Diaconu; Elena Andrese Porumb; Anisia Iuliana Alexa; Alin Codrut Nicolescu; Ilarie Brihan; Camelia Margareta Bogdanici; George Branisteanu; Andreea Dimitriu; Mihail Zemba; Nicoleta Anton; Mihaela Paula Toader; Adrian Grechin; Daniel Constantin Branisteanu
Journal:  Exp Ther Med       Date:  2022-01-05       Impact factor: 2.447

2.  Selenium-Rich Yeast Peptide Fraction Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis in Mice by Inhibiting Inflammation via MAPK and NF-κB Signaling Pathways.

Authors:  Hengke Guo; Min Li; Hongmei Liu
Journal:  Int J Mol Sci       Date:  2022-02-14       Impact factor: 5.923

Review 3.  S100 Proteins as Novel Therapeutic Targets in Psoriasis and Other Autoimmune Diseases.

Authors:  Katarzyna Kurpet; Grażyna Chwatko
Journal:  Molecules       Date:  2022-10-06       Impact factor: 4.927

Review 4.  Experimental Pharmacological Management of Psoriasis.

Authors:  Elena Campione; Terenzio Cosio; Monia Di Prete; Caterina Lanna; Annunziata Dattola; Luca Bianchi
Journal:  J Exp Pharmacol       Date:  2021-07-26

Review 5.  Overview of the molecular determinants contributing to the expression of Psoriasis and Psoriatic Arthritis phenotypes.

Authors:  Valerio Caputo; Claudia Strafella; Andrea Termine; Annunziata Dattola; Sara Mazzilli; Caterina Lanna; Terenzio Cosio; Elena Campione; Giuseppe Novelli; Emiliano Giardina; Raffaella Cascella
Journal:  J Cell Mol Med       Date:  2020-10-31       Impact factor: 5.295
  5 in total

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