| Literature DB >> 31415984 |
Ivana Ivancová1, Denise-Liu' Leone1, Michal Hocek2.
Abstract
Modification of DNA with reactive groups and their post-synthetic transformations are useful for labelling, imaging, bioconjugations and cross-linking with other (bio)molecules. This review summarizes the recent progress in this field and covers transformations of oxo groups, cycloadditions, conjugate additions, alkylations, cross-couplings and other reactions. Examples of applications are given and the practicability and scope of the reactions are discussed.Mesh：
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Year: 2019 PMID： 31415984 DOI： 10.1016/j.cbpa.2019.07.007
Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.822