Semra Koca1, Duru Onan2, Defne Kalaycı3, Nuran Allı4. 1. Ophthalmologist, Department of Ophthalmology, Denizli State Hospital , Denizli, Turkey. 2. Dermatologist, Department of Dermatology, Ankara Numune Training and Research Hospital , Ankara, Turkey. 3. Department of Ophthalmology, Ankara Numune Training and Research Hospital , Ankara, Turkey. 4. Department of Dermatology, Ankara Numune Training and Research Hospital , Ankara, Turkey.
Abstract
PURPOSE: To investigate optical coherence tomography angiography (OCTA) findings in patients with Behçet's disease (BD). METHODS: Ninety-four eyes of 49 patients with BD and 53 eyes of 53 healthy subjects were included. Vascular density (VD), foveal avascular zone (FAZ) area, perifoveal capillary hypoperfusion, perifoveal capillary network disorganization, and FAZ irregularity were analyzed. RESULTS: OCTA revealed retinal VD reduction and higher perifoveal capillary hypoperfusion, perifoveal capillary network disorganization and FAZ irregularity in ocular Behçet's compared to nonocular Behçet's (p = .000). However, compared to normal eyes, there was no difference between any OCTA measurements in nonocular BD patients. The mean area of FAZ was not different in any group (p = .266). In ocular Behçet, visual acuity was inversely correlated with FAZ area and FAZ irregularity. CONCLUSION: Retinal VD decreases and perifoveal microvascular network changes in ocular Behçet's. FAZ irregularity may be a more valuable marker than FAZ area for indicating ocular involvement.
PURPOSE: To investigate optical coherence tomography angiography (OCTA) findings in patients with Behçet's disease (BD). METHODS: Ninety-four eyes of 49patients with BD and 53 eyes of 53 healthy subjects were included. Vascular density (VD), foveal avascular zone (FAZ) area, perifoveal capillary hypoperfusion, perifoveal capillary network disorganization, and FAZ irregularity were analyzed. RESULTS: OCTA revealed retinal VD reduction and higher perifoveal capillary hypoperfusion, perifoveal capillary network disorganization and FAZ irregularity in ocular Behçet's compared to nonocular Behçet's (p = .000). However, compared to normal eyes, there was no difference between any OCTA measurements in nonocular BDpatients. The mean area of FAZ was not different in any group (p = .266). In ocular Behçet, visual acuity was inversely correlated with FAZ area and FAZ irregularity. CONCLUSION:Retinal VD decreases and perifoveal microvascular network changes in ocular Behçet's. FAZ irregularity may be a more valuable marker than FAZ area for indicating ocular involvement.