Literature DB >> 3141392

Cloning and sequencing of a full-length cDNA of mouse N-acetylglucosamine (beta 1-4)galactosyltransferase.

K Nakazawa1, T Ando, T Kimura, H Narimatsu.   

Abstract

A full-length cDNA clone for mouse N-acetylglucosamine (beta 1-4)galactosyltransferase (beta 1-4GT) [EC 2.4.1.90] and several clones diverged from the beta 1-4GT cDNA were isolated from a mouse F9 cDNA library and then sequenced. The beta 1-4GT cDNA has an open reading frame consisting of 399 amino acids. The homology at the amino acid level is 80 and 91% as to the partial sequences of bovine and human milk beta 1-4GT, respectively. The general enzyme structure of the beta 1-4GT seems to be similar to that of a rat beta-galactoside (alpha 2-6) sialyltransferase. Junctions of the common and divergent regions of cDNA have dinucleotides, AG, suggesting that the variety of cDNA clones is generated through alternative splicing.

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Year:  1988        PMID： 3141392     DOI： 10.1093/oxfordjournals.jbchem.a122434

Source DB:  PubMed          Journal:  J Biochem        ISSN： 0021-924X            Impact factor:   3.387


  8 in total

1.  The E1 glycoprotein of an avian coronavirus is targeted to the cis Golgi complex.

Authors:  C E Machamer; S A Mentone; J K Rose; M G Farquhar
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

2.  Expression of bovine beta-1,4-galactosyltransferase cDNA in COS-7 cells.

Authors:  A S Masibay; P K Qasba
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

3.  Murine beta 1,4-galactosyltransferase: both the amounts and structure of the mRNA are regulated during spermatogenesis.

Authors:  N L Shaper; W W Wright; J H Shaper
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

4.  Biosynthesis in vitro of neolactotetraosylceramide by a galactosyltransferase from mouse T-lymphoma: purification and kinetic studies; synthesis of neolacto and polylactosamine core.

Authors:  M Basu; S A Weng; H Tang; F Khan; F Rossi; S Basu
Journal:  Glycoconj J       Date:  1996-06       Impact factor: 2.916

5.  Cell surface and Golgi pools of beta-1,4-galactosyltransferase are differentially regulated during embryonal carcinoma cell differentiation.

Authors:  L C Lopez; C M Maillet; K Oleszkowicz; B D Shur
Journal:  Mol Cell Biol       Date:  1989-06       Impact factor: 4.272

6.  Analysis of the substrate binding sites of human galactosyltransferase by protein engineering.

Authors:  D Aoki; H E Appert; D Johnson; S S Wong; M N Fukuda
Journal:  EMBO J       Date:  1990-10       Impact factor: 11.598

7.  OCH1 encodes a novel membrane bound mannosyltransferase: outer chain elongation of asparagine-linked oligosaccharides.

Authors:  K Nakayama; T Nagasu; Y Shimma; J Kuromitsu; Y Jigami
Journal:  EMBO J       Date:  1992-07       Impact factor: 11.598

8.  Disruption of Smad4 expression in T cells leads to IgA nephropathy-like manifestations.

Authors:  Hiroyuki Inoshita; Byung-Gyu Kim; Michifumi Yamashita; Sung Hee Choi; Yasuhiko Tomino; John J Letterio; Steven N Emancipator
Journal:  PLoS One       Date:  2013-11-04       Impact factor: 3.240
  8 in total

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