Shivanthan Shanthikumar1,2,3, John Massie4,5,6, Sarath Ranganathan4,5,6, Maren Schuhmann7,8, Ralf Eberhardt7,8, Louis B Irving9,10, Felix J F Herth7,8, Daniel P Steinfort9,10. 1. Respiratory and Sleep Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia, shivanthan.shanthikumar@rch.org.au. 2. Respiratory Diseases, Murdoch Children's Research Institute, Melbourne, Victoria, Australia, shivanthan.shanthikumar@rch.org.au. 3. Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia, shivanthan.shanthikumar@rch.org.au. 4. Respiratory and Sleep Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia. 5. Respiratory Diseases, Murdoch Children's Research Institute, Melbourne, Victoria, Australia. 6. Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia. 7. Department of Pneumology and Critical Care Medicine, Thoraxklinik, Heidelberg, Germany. 8. Translational Lung Research Center, University of Heidelberg, Heidelberg, Germany. 9. Department of Respiratory and Sleep Medicine, Royal Melbourne Hospital, Parkville, Victoria, Australia. 10. Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia.
Abstract
INTRODUCTION: In adults, linear endobronchial ultrasound (EBUS) is the preferred modality to sample intrathoracic adenopathy and radial EBUS is a useful tool to biopsy peripheral pulmonary nodules. Utility in children is less well known. OBJECTIVES: The objective of this study was to review the EBUS experience of two specialist centres to better define the current role of EBUS in paediatric practice. METHODS: A retrospective record review of EBUS procedures undertaken in patients aged 0-17 years at the Royal Children's Hospital (Melbourne, Australia) and Thoraxklinik (Heidelberg, Germany) was performed. Data extracted included patient demographics, clinical presentation, bronchoscope (size and model), EBUS technique used, pathologic results, need for further invasive investigation, and complications. RESULTS: Between 2008 and 2017, ten EBUS procedures were performed (6 linear EBUS and 4 radial EBUS). No complications were reported. Linear EBUS was performed on subjects who were between 4 and 15 years old, with a 100% diagnostic yield. Radial EBUS was non-diagnostic in three cases of non-malignant disease. In one case, it was used successfully for imaging alone. CONCLUSION: Both linear and radial EBUS are safe and feasible in children. Diagnostic yield of linear EBUS was 100%. Radial EBUS did not demonstrate utility, likely reflecting the pathologies of underlying parenchymal masses in paediatric populations.
INTRODUCTION: In adults, linear endobronchial ultrasound (EBUS) is the preferred modality to sample intrathoracic adenopathy and radial EBUS is a useful tool to biopsy peripheral pulmonary nodules. Utility in children is less well known. OBJECTIVES: The objective of this study was to review the EBUS experience of two specialist centres to better define the current role of EBUS in paediatric practice. METHODS: A retrospective record review of EBUS procedures undertaken in patients aged 0-17 years at the Royal Children's Hospital (Melbourne, Australia) and Thoraxklinik (Heidelberg, Germany) was performed. Data extracted included patient demographics, clinical presentation, bronchoscope (size and model), EBUS technique used, pathologic results, need for further invasive investigation, and complications. RESULTS: Between 2008 and 2017, ten EBUS procedures were performed (6 linear EBUS and 4 radial EBUS). No complications were reported. Linear EBUS was performed on subjects who were between 4 and 15 years old, with a 100% diagnostic yield. Radial EBUS was non-diagnostic in three cases of non-malignant disease. In one case, it was used successfully for imaging alone. CONCLUSION: Both linear and radial EBUS are safe and feasible in children. Diagnostic yield of linear EBUS was 100%. Radial EBUS did not demonstrate utility, likely reflecting the pathologies of underlying parenchymal masses in paediatric populations.
Authors: Gaetano Rea; Marco Sperandeo; Roberta Lieto; Marialuisa Bocchino; Carla Maria Irene Quarato; Beatrice Feragalli; Tullio Valente; Giulia Scioscia; Ernesto Giuffreda; Maria Pia Foschino Barbaro; Donato Lacedonia Journal: Front Med (Lausanne) Date: 2021-12-10