Rui Zhao1, Chaoyu Gu2, Qiuxiang Zhang3,4, Wei Zhou1, Guijuan Feng5, Xingmei Feng5, Chen Dong1,6, Zhifeng Gu3,6. 1. Department of Nursing, Affiliated Hospital of Nantong University, Nantong, China. 2. Medical College, Nantong University, Nantong, China. 3. Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong, China. 4. Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. 5. Department of Stomatology, Affiliated Hospital of Nantong University, Nantong, China. 6. Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Abstract
OBJECTIVE: To evaluate the prevalence and severity of periodontal disease in Chinese rheumatoid arthritis patients. SUBJECTS AND METHODS: This cross-sectional study included 128 RA and 109 healthy controls. Two dentists conducted periodontal status including Plaque index (PI), Gingival index (GI), pocket probing depths (PPDs), Clinical attachment level (CAL) and Bleeding on probing (BOP) independently. Sociodemographic, lifestyle, clinical parameters and use of medication were assessed. Data were analyzed by Student's t test, χ2 test, Wilcoxin-Mann- Whitney's test, Correlational Analysis, univariate or multivariate logistic regression. RESULTS: The periodontal status was significantly worse in RA, especially the condition of dental and gingival status. RA had 4.68-fold. After adjusted potential risk factors, RA had 10.26-fold. The independent variable related to GI was DAS28 (p = .05) negatively, to the contrary, ESR (p = .013) was positively associated; the independent variable positively and related to periodontitis was educational level (p = .021) and anti-CCP positivity (p = .002). Through multivariate logistic regression, age and swollen joint were the independent variable related to periodontitis of RA (OR 1.087, p = .044) and (OR 1.560, p = .008) respectively. CONCLUSIONS: Chinese RA patients show higher odds of PD. It is important to take early interventions in combination with medical therapy.
OBJECTIVE: To evaluate the prevalence and severity of periodontal disease in Chinese rheumatoid arthritispatients. SUBJECTS AND METHODS: This cross-sectional study included 128 RA and 109 healthy controls. Two dentists conducted periodontal status including Plaque index (PI), Gingival index (GI), pocket probing depths (PPDs), Clinical attachment level (CAL) and Bleeding on probing (BOP) independently. Sociodemographic, lifestyle, clinical parameters and use of medication were assessed. Data were analyzed by Student's t test, χ2 test, Wilcoxin-Mann- Whitney's test, Correlational Analysis, univariate or multivariate logistic regression. RESULTS: The periodontal status was significantly worse in RA, especially the condition of dental and gingival status. RA had 4.68-fold. After adjusted potential risk factors, RA had 10.26-fold. The independent variable related to GI was DAS28 (p = .05) negatively, to the contrary, ESR (p = .013) was positively associated; the independent variable positively and related to periodontitis was educational level (p = .021) and anti-CCP positivity (p = .002). Through multivariate logistic regression, age and swollen joint were the independent variable related to periodontitis of RA (OR 1.087, p = .044) and (OR 1.560, p = .008) respectively. CONCLUSIONS: Chinese RApatients show higher odds of PD. It is important to take early interventions in combination with medical therapy.
Authors: Marcela F Moura; Luís O M Cota; Tarcília A Silva; Sheila C Cortelli; Gilda A Ferreira; Marina M López; José R Cortelli; Fernando O Costa Journal: Odontology Date: 2020-11-03 Impact factor: 2.634