Literature DB >> 31410784

The Role of Patient-Physician Communication on the Use of Hydroxyurea in Adult Patients with Sickle Cell Disease.

Sarah M Jabour1, Sara Beachy2, Shayna Coburn3,4, Sophie Lanzkron5, Michelle N Eakin6.   

Abstract

OBJECTIVE: This qualitative study analyzed the perspective of patients living with sickle cell disease (SCD) on their process of deciding whether to take hydroxyurea (HU), and the role of physician communication in patients' decision-making process.
METHODS: From October 2015 to July 2016, we conducted semi-structured interviews among patients with SCD (N = 20) that were audio-recorded and transcribed. Participants were ≥ 18 years old, a patient of an urban adult sickle cell center, able to provide informed consent, and English-speaking. We iteratively developed codes and used thematic analysis to organize the key themes.
RESULTS: Most participants were female (65%), middle aged (M = 44, SD = 12.2), and 55% were prescribed HU for an average of 10.4 (SD = 4.7) years. Participants described 3 key factors that influenced their decision regarding HU treatment: (1) lifestyle, (2) health status, and (3) HU characteristics. Four themes emerged about provider communication and HU treatment decisions: (1) provider's advisement, (2) shared decision-making, (3) "wrestled," and (4) not feeling heard.
CONCLUSION: Providers who engaged in shared decision-making empowered participants to decide whether to start HU treatment. Participants who felt their providers were not listening to their concerns expressed disengaging from HU treatment. During discussions about HU with patients living with SCD, providers must understand the multi-faceted aspects that impact patients' decision and empower patients to engage in such discussions. Further research is needed to understand the role of shared decision-making among patients with SCD to improve management of SCD.

Entities:  

Keywords:  Patient-provider communication; Shared decision-making, hydroxyurea; Sickle cell disease

Mesh:

Substances:

Year:  2019        PMID: 31410784      PMCID: PMC6832819          DOI: 10.1007/s40615-019-00625-5

Source DB:  PubMed          Journal:  J Racial Ethn Health Disparities        ISSN: 2196-8837


  40 in total

1.  National Institutes of Health Consensus Development Conference statement: hydroxyurea treatment for sickle cell disease.

Authors:  Otis W Brawley; Llewellyn J Cornelius; Linda R Edwards; Vanessa Northington Gamble; Bettye L Green; Charles Inturrisi; Andra H James; Danielle Laraque; Magda Mendez; Carolyn J Montoya; Brad H Pollock; Lawrence Robinson; Aaron P Scholnik; Melissa Schori
Journal:  Ann Intern Med       Date:  2008-05-05       Impact factor: 25.391

2.  The number of people with sickle-cell disease in the United States: national and state estimates.

Authors:  David C Brousseau; Julie A Panepinto; Mark Nimmer; Raymond G Hoffmann
Journal:  Am J Hematol       Date:  2010-01       Impact factor: 10.047

3.  Health-related quality of life and adherence to hydroxyurea in adolescents and young adults with sickle cell disease.

Authors:  Sherif M Badawy; Alexis A Thompson; Jin-Shei Lai; Frank J Penedo; Karen Rychlik; Robert I Liem
Journal:  Pediatr Blood Cancer       Date:  2016-11-28       Impact factor: 3.167

4.  Examining the characteristics and beliefs of hydroxyurea users and nonusers among adults with sickle cell disease.

Authors:  Carlton Haywood; Mary Catherine Beach; Shawn Bediako; C Patrick Carroll; Lakshmi Lattimer; Dasheema Jarrett; Sophie Lanzkron
Journal:  Am J Hematol       Date:  2011-01       Impact factor: 10.047

5.  Barriers to hydroxyurea adherence and health-related quality of life in adolescents and young adults with sickle cell disease.

Authors:  Sherif M Badawy; Alexis A Thompson; Frank J Penedo; Jin-Shei Lai; Karen Rychlik; Robert I Liem
Journal:  Eur J Haematol       Date:  2017-04-17       Impact factor: 2.997

6.  Perceived discrimination in health care is associated with a greater burden of pain in sickle cell disease.

Authors:  Carlton Haywood; Marie Diener-West; John Strouse; C Patrick Carroll; Shawn Bediako; Sophie Lanzkron; Jennifer Haythornthwaite; Gladys Onojobi; Mary Catherine Beach
Journal:  J Pain Symptom Manage       Date:  2014-04-15       Impact factor: 3.612

7.  Perceived discrimination, patient trust, and adherence to medical recommendations among persons with sickle cell disease.

Authors:  Carlton Haywood; Sophie Lanzkron; Shawn Bediako; John J Strouse; Jennifer Haythornthwaite; C Patrick Carroll; Marie Diener-West; Gladys Onojobi; Mary Catherine Beach
Journal:  J Gen Intern Med       Date:  2014-09-10       Impact factor: 5.128

8.  Provider barriers to hydroxyurea use in adults with sickle cell disease: a survey of the Sickle Cell Disease Adult Provider Network.

Authors:  Sophie Lanzkron; Carlton Haywood; Kathryn L Hassell; Cynthia Rand
Journal:  J Natl Med Assoc       Date:  2008-08       Impact factor: 1.798

9.  Development of a Hydroxyurea Decision Aid for Parents of Children With Sickle Cell Anemia.

Authors:  Lori E Crosby; Ashley Walton; Lisa M Shook; Russell E Ware; Marsha Treadwell; Kay L Saving; Maria Britto; James Peugh; Emily McTate; Suzette Oyeku; Cara Nwankwo; William B Brinkman
Journal:  J Pediatr Hematol Oncol       Date:  2019-01       Impact factor: 1.289

10.  Shared decision making for hydroxyurea treatment initiation in children with sickle cell anemia.

Authors:  Lori E Crosby; Lisa M Shook; Russell E Ware; William B Brinkman
Journal:  Pediatr Blood Cancer       Date:  2014-10-12       Impact factor: 3.167

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