Ziyan Feng1, Yifei Fan1, Jiusi Guo2, Weili Fu3. 1. West China School of Medicine, Sichuan University, Chengdu Sichuan, 610041, P.R.China. 2. West China School of Stomatology, Sichuan University, Chengdu Sichuan, 610041, P.R.China. 3. Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China.foxwin2008@163.com.
Abstract
OBJECTIVE: To summarize and analyze the research progress of scaffold materials used in tissue engineered meniscus. METHODS: The classification and bionics design of scaffold materials were summarized by consulting domestic and foreign literature related to the research of tissue engineered meniscus in recent years. RESULTS: Tissue engineered meniscus scaffolds can be roughly classified into synthetic polymers, hydrogels, extracellular matrix components, and tissue derived materials. These different materials have different characteristics, so the use of a single material has its unique disadvantages, and the use of a variety of materials composite scaffolds can learn from each other, which is a hot research area at present. In addition to material selection, material processing methods are also the focus of research. At the same time, according to the morphological structure and mechanical characteristics of the meniscus, the bionic design of tissue engineered meniscus scaffolds has great potential. CONCLUSION: At present, there are many kinds of scaffold materials for tissue engineered meniscus. However, there is no material that can completely simulate the natural meniscus, and further research of scaffold materials is still needed.
OBJECTIVE: To summarize and analyze the research progress of scaffold materials used in tissue engineered meniscus. METHODS: The classification and bionics design of scaffold materials were summarized by consulting domestic and foreign literature related to the research of tissue engineered meniscus in recent years. RESULTS: Tissue engineered meniscus scaffolds can be roughly classified into synthetic polymers, hydrogels, extracellular matrix components, and tissue derived materials. These different materials have different characteristics, so the use of a single material has its unique disadvantages, and the use of a variety of materials composite scaffolds can learn from each other, which is a hot research area at present. In addition to material selection, material processing methods are also the focus of research. At the same time, according to the morphological structure and mechanical characteristics of the meniscus, the bionic design of tissue engineered meniscus scaffolds has great potential. CONCLUSION: At present, there are many kinds of scaffold materials for tissue engineered meniscus. However, there is no material that can completely simulate the natural meniscus, and further research of scaffold materials is still needed.
Entities:
Keywords:
Tissue engineered meniscus; bionic design; scaffold material
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