Literature DB >> 3140739

Effect of misoprostol on fat malabsorption in cystic fibrosis.

P J Robinson1, P D Sly, A L Smith.   

Abstract

Misoprostol, a synthetic prostaglandin that is known to reduce gastric acid production and stimulate duodenal bicarbonate production, was evaluated in 22 patients with cystic fibrosis. In those patients who had greater than 10% fat malabsorption while taking pancrease the addition of misoprostol significantly reduced the degree of fat malabsorption.

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Year:  1988        PMID: 3140739      PMCID: PMC1779094          DOI: 10.1136/adc.63.9.1081

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  3 in total

1.  Intraduodenal events in cystic fibrosis.

Authors:  A M Weber; C C Roy
Journal:  J Pediatr Gastroenterol Nutr       Date:  1984       Impact factor: 2.839

2.  Secretin pancreozymin stimulation test and confirmation of the diagnosis of cystic fibrosis.

Authors:  L T Wong; S Turtle; A G Davidson
Journal:  Gut       Date:  1982-09       Impact factor: 23.059

3.  Gastric acid hypersecretion in cystic fibrosis.

Authors:  K L Cox; J N Isenberg; M E Ament
Journal:  J Pediatr Gastroenterol Nutr       Date:  1982       Impact factor: 2.839

  3 in total
  6 in total

Review 1.  Control of malabsorption in cystic fibrosis.

Authors:  J M Littlewood; S P Wolfe
Journal:  Paediatr Drugs       Date:  2000 May-Jun       Impact factor: 3.022

2.  Duodenal pH in cystic fibrosis and its relationship to fat malabsorption.

Authors:  P J Robinson; A L Smith; P D Sly
Journal:  Dig Dis Sci       Date:  1990-10       Impact factor: 3.199

3.  Omeprazole, a proton pump inhibitor, improves residual steatorrhoea in cystic fibrosis patients treated with high dose pancreatic enzymes.

Authors:  Marijke Proesmans; Kris De Boeck
Journal:  Eur J Pediatr       Date:  2003-09-17       Impact factor: 3.183

4.  Upregulation of COX-1 and COX-2 in nasal polyps in cystic fibrosis.

Authors:  J Roca-Ferrer; L Pujols; S Gartner; A Moreno; F Pumarola; J Mullol; N Cobos; C Picado
Journal:  Thorax       Date:  2006-03-03       Impact factor: 9.139

Review 5.  Drug therapies for reducing gastric acidity in people with cystic fibrosis.

Authors:  Sze May Ng; Helen S Moore
Journal:  Cochrane Database Syst Rev       Date:  2016-08-22

6.  Drug therapies for reducing gastric acidity in people with cystic fibrosis.

Authors:  Sze May Ng; Helen S Moore
Journal:  Cochrane Database Syst Rev       Date:  2021-04-27
  6 in total

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