Francisco Javier García-Martínez1,2, Eva Vilarrasa Rull3, Laura Salgado-Boquete4, Antonio Martorell5, Jose Carlos Pascual6, Ángela Hernández-Martín7, Catiana Silvente8, Cristina Ciudad-Blanco9, Eva Andrés Esteban10, F Alfageme-Roldán11. 1. Dermatology Department, Clínica Universidad de Navarra, Madrid, Spain. 2. Hidradenitis Suppurativa and Cutaneous Ultrasound Unit, Hospital Universitario del Sureste, Madrid, Spain. 3. Dermatology Department, Hospital Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, Spain. 4. Dermatology Department, Complexo Hospitalario de Pontevedra, Pontevedra, Spain. 5. Dermatology Department, Hospital de Manises, Valencia, Spain. 6. Dermatology Department, Hospital General de Alicante, Alicante, Spain. 7. Dermatology Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain. 8. Dermatology Department, Hospital Infanta Leonor, Madrid, Spain. 9. Dermatology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain. 10. Preventive Medicine Department, Universidad Jaume I de Castellón, Castellón, Spain. 11. Dermatology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Abstract
BACKGROUND AND OBJECTIVES: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the follicular unit characterized by recurrent, painful, skin lesions including inflammatory nodules, abscesses, tunnels, and mutilating scarring. Intralesional corticosteroids injection (ICI) for HS has received little attention in the scientific literature. We evaluate the clinical response of ICI in acute and chronic HS lesions and aim to identify new applications of ultrasound-assisted procedures in HS management. PATIENTS AND METHODS: An observational, retrospective, multicenter study of HS patients treated with ICI was conducted from January 1 to August 1, 2015. We collected 98 HS patients. A total of 135 individual lesions were infiltrated, including non-inflammatory nodules, inflammatory nodules abscesses and fistulous tracts. RESULTS: Complete response was reached in 95 lesions (70.37%), 34 showed partial response (25.19%) and 6 (4.44%) were non-response. A total of 105 individual lesions underwent sonographic scan before ICI. CONCLUSION: Clinical experience supported the use of ICI for individual lesions. Our results showed that ICI is a useful treatment to control in acute and recalcitrant HS lesions. Response rates improve significantly if lesions are previously evaluated with HFUS.
BACKGROUND AND OBJECTIVES: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the follicular unit characterized by recurrent, painful, skin lesions including inflammatory nodules, abscesses, tunnels, and mutilating scarring. Intralesional corticosteroids injection (ICI) for HS has received little attention in the scientific literature. We evaluate the clinical response of ICI in acute and chronic HS lesions and aim to identify new applications of ultrasound-assisted procedures in HS management. PATIENTS AND METHODS: An observational, retrospective, multicenter study of HS patients treated with ICI was conducted from January 1 to August 1, 2015. We collected 98 HS patients. A total of 135 individual lesions were infiltrated, including non-inflammatory nodules, inflammatory nodules abscesses and fistulous tracts. RESULTS: Complete response was reached in 95 lesions (70.37%), 34 showed partial response (25.19%) and 6 (4.44%) were non-response. A total of 105 individual lesions underwent sonographic scan before ICI. CONCLUSION: Clinical experience supported the use of ICI for individual lesions. Our results showed that ICI is a useful treatment to control in acute and recalcitrant HS lesions. Response rates improve significantly if lesions are previously evaluated with HFUS.