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Literature DB >> 31402061

cAMPing out with the keepers of the gate: Adenylyl cyclases get cozy with Orai.

Abstract

Calcium and cyclic AMP form the cornerstones of two ancient signaling systems represented in nearly every kingdom of life. Not surprisingly, these old and ubiquitous messenger molecules have co-evolved multiple means to regulate one another. Zhang et al. describe a new twist on this theme related to the intimate union between the calcium-activated adenylyl cyclase, AC8, and the store-operated Ca2+ channel, Orai1. Published by Elsevier Ltd.

Entities: CellLine Chemical Disease Gene Species

Keywords: Adenylyl cyclase; Calcium channels; Cyclic AMP; Electrophysiology; Patch clamp

Mesh：

Substances：

Year: 2019 PMID： 31402061 PMCID： PMC7427263 DOI： 10.1016/j.ceca.2019.102054

Source DB: PubMed Journal: Cell Calcium ISSN： 0143-4160 Impact factor: 6.817

10 in total

1. Alternative translation initiation gives rise to two isoforms of Orai1 with distinct plasma membrane mobilities.

Authors: Miwako Fukushima; Takuro Tomita; Agnes Janoshazi; James W Putney
Journal: J Cell Sci Date: 2012-05-28 Impact factor: 5.285

2. STIM1 activation of adenylyl cyclase 6 connects Ca²⁺ and cAMP signaling during melanogenesis.

Authors: Rajender K Motiani; Jyoti Tanwar; Desingu Ayyappa Raja; Ayushi Vashisht; Shivangi Khanna; Sachin Sharma; Sonali Srivastava; Sridhar Sivasubbu; Vivek T Natarajan; Rajesh S Gokhale
Journal: EMBO J Date: 2018-01-08 Impact factor: 11.598

3. A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling.

Authors: Monica Soto-Velasquez; Michael P Hayes; Aktan Alpsoy; Emily C Dykhuizen; Val J Watts
Journal: Mol Pharmacol Date: 2018-06-27 Impact factor: 4.436

Review 4. Store-operated Ca²⁺-entry and adenylyl cyclase.

Authors: Dermot M F Cooper
Journal: Cell Calcium Date: 2015-04-22 Impact factor: 6.817

5. Direct binding between Orai1 and AC8 mediates dynamic interplay between Ca2+ and cAMP signaling.

Authors: Debbie Willoughby; Katy L Everett; Michelle L Halls; Jonathan Pacheco; Philipp Skroblin; Luis Vaca; Enno Klussmann; Dermot M F Cooper
Journal: Sci Signal Date: 2012-04-10 Impact factor: 8.192

6. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.

Authors: Stefan Feske; Yousang Gwack; Murali Prakriya; Sonal Srikanth; Sven-Holger Puppel; Bogdan Tanasa; Patrick G Hogan; Richard S Lewis; Mark Daly; Anjana Rao
Journal: Nature Date: 2006-04-02 Impact factor: 49.962

7. Store-operated cyclic AMP signalling mediated by STIM1.

Authors: Konstantinos Lefkimmiatis; Meera Srikanthan; Isabella Maiellaro; Mary Pat Moyer; Silvana Curci; Aldebaran M Hofer
Journal: Nat Cell Biol Date: 2009-03-15 Impact factor: 28.824

8. Altered store operated calcium entry increases cyclic 3',5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes.

Authors: Carlo Spirli; Luigi Locatelli; Romina Fiorotto; Carola M Morell; Luca Fabris; Tullio Pozzan; Mario Strazzabosco
Journal: Hepatology Date: 2012-03 Impact factor: 17.425

9. Termination and activation of store-operated cyclic AMP production.

Authors: Isabella Maiellaro; Konstantinos Lefkimmiatis; Mary Pat Moyer; Silvana Curci; Aldebaran M Hofer
Journal: J Cell Mol Med Date: 2012-11 Impact factor: 5.310

10. A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction.

Authors: Xuexin Zhang; Trayambak Pathak; Ryan Yoast; Scott Emrich; Ping Xin; Robert M Nwokonko; Martin Johnson; Shilan Wu; Céline Delierneux; Maxime Gueguinou; Nadine Hempel; James W Putney; Donald L Gill; Mohamed Trebak
Journal: Nat Commun Date: 2019-04-29 Impact factor: 14.919