| Literature DB >> 31401420 |
Martha Stathaki1, Maria Evanthia Stamatiou1, George Magioris1, Spyridon Simantiris1, Nikolaos Syrigos1, Spyridon Dourakis2, Michael Koutsilieris1, Athanasios Armakolas3.
Abstract
Kisspeptins are a family of neuropeptides that are known to be critical in puberty initiation and ovulation. Apart from that kisspeptin derived peptides (KPs) are also known for their antimetastatic activities in several malignancies. Herein we report recent evidence of the role of kisspeptins in cancer biology and we examine the prospective of targeting the kisspeptin pathways leading to a better prognosis in patients with malignant diseases.Entities:
Keywords: Cancer; KiSS-1; KiSS-1R; Kisspeptin; Metastases inhibition
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Year: 2019 PMID： 31401420 DOI： 10.1016/j.critrevonc.2019.07.015
Source DB: PubMed Journal: Crit Rev Oncol Hematol ISSN： 1040-8428 Impact factor: 6.312