| Literature DB >> 31400876 |
Karl Magtibay1, Andreu Porta-Sánchez2, Shouvik K Haldar3, Don Curtis Deno4, Stéphane Massé1, Kumaraswamy Nanthakumar5.
Abstract
Omnipolar electrograms (EGMs) make use of biophysical electric fields that accompany activation along the surface of the myocardium. A grid-like electrode array provides bipolar signals in orthogonal directions to deliver catheter-orientation-independent assessments of cardiac electrophysiology. Studies with myocyte monolayers, isolated animal and human hearts, and anesthetized animals validated the tenets of omnipolar EGMs. The combination of information from omnipolar-based activation vectors and voltages may aid in localizing areas of scar, lesion gaps, wavefront disorganization, and fractionation or collision during arrhythmias. The goal of omnipolar EGMs is to better characterize myocardium through reintroducing electrogram direction related fundamentals of cardiac electrophysiology.Entities:
Keywords: Activation direction; Atrial fibrillation; Cardiac mapping; Conduction velocity; Electrogram direction; Omnipolar; Ventricular tachycardia; Wavefront orientation
Mesh:
Year: 2019 PMID: 31400876 DOI: 10.1016/j.ccep.2019.05.003
Source DB: PubMed Journal: Card Electrophysiol Clin ISSN: 1877-9182