Literature DB >> 31400224

Long-term outcomes and five-year recurrence-free survival curves after native-tissue prolapse repair.

Giuseppe Deo1, Davide P Bernasconi1, Alice Cola1,2, Stefania Palmieri1,2, Federico Spelzini3, Rodolfo Milani2, Stefano Manodoro3, Matteo Frigerio1,2.   

Abstract

OBJECTIVE: To evaluate the long-term objective and subjective outcomes to build recurrence-free survival curves after mesh-free uterosacral ligament suspension and to evaluate the long-term impact of prognostic factors on outcome measures.
METHODS: A retrospective study analyzed 5-year follow-up after repair of primary prolapse through high uterosacral ligament suspension. Bulging symptoms and post-operative prolapse stage II or above were considered subjective and objective recurrences, respectively. The cumulative proportion of relapse-free patients in time was analyzed by Kaplan-Meier curves.
RESULTS: A total of 353 women were analyzed. Five-year recurrence rates were 15.0% for objective recurrence, 13.0% for subjective recurrence, and 4.0% for the combined objective and subjective recurrences. Premenopausal status was shown to be a risk factor for anatomic (P=0.022), symptomatic (P=0.001), and combined (P=0.047) recurrence. Conversely, anterior repair was shown to be a protective factor for symptomatic (P=0.012) and combined (P=0.002) recurrence. Most of the recurrences occurred within 2 years after surgery.
CONCLUSION: Long-term outcomes after high uterosacral ligament suspension were satisfactory. Premenopausal status and lack of anterior repair represented risk factors for recurrence in the long term.
© 2019 International Federation of Gynecology and Obstetrics.

Entities:  

Keywords:  Long-term follow-up; Native-tissue repair; Prolapse surgery; Recurrence; Risk factors; Uterosacral ligament suspension

Mesh:

Year:  2019        PMID: 31400224     DOI: 10.1002/ijgo.12938

Source DB:  PubMed          Journal:  Int J Gynaecol Obstet        ISSN: 0020-7292            Impact factor:   3.561


  1 in total

1.  Native-tissue prolapse repair: Efficacy and adverse effects of uterosacral ligaments suspension at 10-year follow up.

Authors:  Alice Cola; Giuseppe Marino; Rodolfo Milani; Marta Barba; Silvia Volontè; Federico Spelzini; Stefano Manodoro; Matteo Frigerio
Journal:  Int J Gynaecol Obstet       Date:  2022-02-08       Impact factor: 4.447

  1 in total

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