Literature DB >> 3139602

Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. II. Structure determination.

S Yoshida1, H Naganawa, T Aoyagi, T Takeuchi, H Umezawa.   

Abstract

Benadrostin, a new inhibitor of poly(ADP-ribose) synthetase, has been isolated from the culture broth of Streptomyces flavovirens MH499-O'F1. The structure of benadrostin was defined as 8-hydroxy-2H-1,3-benzoxazine-2,4-dione by an analysis of spectral properties and chemical studies of benadrostin and its derivatives.

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Year:  1988        PMID： 3139602     DOI： 10.7164/antibiotics.41.1015

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  2 in total

1.  RK-144171, a new benadrostin derivative produced by Streptomyces sp. RK88-1441.

Authors:  Jun-Pil Jang; Shunji Takahashi; Yushi Futamura; Toshihiko Nogawa; Jae-Hyuk Jang; Jong Seog Ahn; Hiroyuki Osada
Journal:  J Antibiot (Tokyo)       Date:  2016-06-08       Impact factor: 2.649

2.  Biodiversity, Anti-Trypanosomal Activity Screening, and Metabolomic Profiling of Actinomycetes Isolated from Mediterranean Sponges.

Authors:  Cheng Cheng; Lynsey MacIntyre; Usama Ramadan Abdelmohsen; Hannes Horn; Paraskevi N Polymenakou; RuAngelie Edrada-Ebel; Ute Hentschel
Journal:  PLoS One       Date:  2015-09-25       Impact factor: 3.240
  2 in total

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