Literature DB >> 31393972

Correction: Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin.

Jin Huei Wong, Mohammad Alfatah, Kiat Whye Kong, Shawn Hoon, Wan Lin Yeo, Kuan Chieh Ching, Corinna Jie Hui Goh, Mingzi M Zhang, Yee Hwee Lim, Fong Tian Wong, Prakash Arumugam.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0218189.].

Entities:  

Year:  2019        PMID: 31393972      PMCID: PMC6687108          DOI: 10.1371/journal.pone.0221074

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


Fig 10 is incorrect. Please see the correct Fig 10 here.
Fig 10

Auroramycin causes hyperpolarization of yeast cells.

(A)diS-C3(3) fluorescence of wild type AH109 yeast cells suspensions at different concentrations of amiodarone. (B)diS-C3(3) fluorescence of wild type AH109 yeast cells suspensions at different concentrations of auroramycin. (C)diS-C3(3) fluorescence of wild type AH109 yeast cells suspensions at different concentrations of auroramycin-aglycon. (D)Ratio of fluorescence at 585 nm to 575 nm is plotted for various cultures treated in A-C. Error bars (n = 3 Mean ± S.D) are indicated in the plot. Asterisks indicate statistical significance of fluorescence ratios for amiodarone/auroramycin-treated cells versus DMSO-treated cells, as determined by the Student’s t test (**, 2-sided P < 0.01 and *, 2-sided P< 0.05). This experiment was performed twice and data from one experiment are shown here.

Auroramycin causes hyperpolarization of yeast cells.

(A)diS-C3(3) fluorescence of wild type AH109 yeast cells suspensions at different concentrations of amiodarone. (B)diS-C3(3) fluorescence of wild type AH109 yeast cells suspensions at different concentrations of auroramycin. (C)diS-C3(3) fluorescence of wild type AH109 yeast cells suspensions at different concentrations of auroramycin-aglycon. (D)Ratio of fluorescence at 585 nm to 575 nm is plotted for various cultures treated in A-C. Error bars (n = 3 Mean ± S.D) are indicated in the plot. Asterisks indicate statistical significance of fluorescence ratios for amiodarone/auroramycin-treated cells versus DMSO-treated cells, as determined by the Student’s t test (**, 2-sided P < 0.01 and *, 2-sided P< 0.05). This experiment was performed twice and data from one experiment are shown here.
  1 in total

1.  Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin.

Authors:  Jin Huei Wong; Mohammad Alfatah; Kiat Whye Kong; Shawn Hoon; Wan Lin Yeo; Kuan Chieh Ching; Corinna Jie Hui Goh; Mingzi M Zhang; Yee Hwee Lim; Fong Tian Wong; Prakash Arumugam
Journal:  PLoS One       Date:  2019-06-10       Impact factor: 3.240

  1 in total

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