Literature DB >> 3139259

Massive somatodendritic sprouting of cortical neurons in Alzheimer's disease.

Y Ihara1.   

Abstract

In addition to neurofibrillary tangles and senile plaques, antibodies to human tau revealed extensive tau-immunoreactive meshworks in layers III and V of the neocortex affected with Alzheimer's disease. The meshworks consisted of innumerable abnormally curly fibers, which were coming from somata and dendrites of pyramidal cells. Their morphological appearance suggests that those curly fibers represent somatodendritic sprouting.

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Year:  1988        PMID: 3139259     DOI: 10.1016/0006-8993(88)90293-4

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  64 in total

1.  Ultrastructure of the neuropil threads in the Alzheimer brain: their dendritic origin and accumulation in the senile plaques.

Authors:  H Yamaguchi; Y Nakazato; M Shoji; Y Ihara; S Hirai
Journal:  Acta Neuropathol       Date:  1990       Impact factor: 17.088

2.  Evidence that neurofibrillary tangles undergo glial modification.

Authors:  K Ikeda; H Akiyama; C Haga; S Haga
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

3.  Massive accumulation of modified tau and severe depletion of normal tau characterize the cerebral cortex and white matter of Alzheimer's disease. Demonstration using the hydrated autoclaving method.

Authors:  R W Shin; T Iwaki; T Kitamoto; Y Sato; J Tateishi
Journal:  Am J Pathol       Date:  1992-04       Impact factor: 4.307

4.  SP-40,40 is a constituent of Alzheimer's amyloid.

Authors:  N H Choi-Miura; Y Ihara; K Fukuchi; M Takeda; Y Nakano; T Tobe; M Tomita
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

5.  Immunocytochemical and ultrastructural studies of neuronal and oligodendroglial cytoplasmic inclusions in multiple system atrophy. 1. Neuronal cytoplasmic inclusions.

Authors:  K Arima; S Murayama; M Mukoyama; T Inose
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

6.  Immunocytochemical and ultrastructural studies of neuronal and oligodendroglial cytoplasmic inclusions in multiple system atrophy. 2. Oligodendroglial cytoplasmic inclusions.

Authors:  S Murayama; K Arima; Y Nakazato; J Satoh; M Oda; T Inose
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

7.  Lack of ubiquitin immunoreactivities at both ends of neuropil threads. Possible bidirectional growth of neuropil threads.

Authors:  T Iwatsubo; M Hasegawa; Y Esaki; Y Ihara
Journal:  Am J Pathol       Date:  1992-02       Impact factor: 4.307

8.  Strategies for diminishing katanin-based loss of microtubules in tauopathic neurodegenerative diseases.

Authors:  Haruka Sudo; Peter W Baas
Journal:  Hum Mol Genet       Date:  2010-11-30       Impact factor: 6.150

9.  Curly fibers are tau-positive strands in the pre- and post-synaptic neurites, consisting of paired helical filaments: observations by the freeze-etch and replica method.

Authors:  K Ohtsubo; N Izumiyama; S Kuzuhara; H Mori; H Shimada
Journal:  Acta Neuropathol       Date:  1990       Impact factor: 17.088

10.  Ultrastructural and immunohistochemical study of degenerate neurite-bearing ghost tangles.

Authors:  K Ikeda; C Haga; S Oyanagi; S Iritani; K Kosaka
Journal:  J Neurol       Date:  1992-04       Impact factor: 4.849

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