Bhoomika Sharma1, Asha Verma2, Chandrabhan Meena2, Anil Gurjar3, Arpita Chakraborty1, Ankita Srivastav1. 1. Department of Obstetrics and Gynaecology, Zenana Hospital, S.M.S. Medical College Jaipur, 5/203 Swami Vivekanand Nagar, Kota, Rajasthan India. 2. 2Department of Obstetrics and Gynaecology, Zenana Hospital, S.M.S. Medical College Jaipur, Imliphatak, Jaipur, Rajasthan India. 3. 3Department of Obstetrics and Gynaecology, Zenana Hospital, S.M.S. Medical College Jaipur, Zenana Hospital Campus, Jaipur, Rajasthan India.
Abstract
AIM: Aim of the study is to evaluate the myocardial performance index in intrauterine growth restricted fetuses and compare this index with appropriate for gestational age fetuses. MATERIALS & METHODS: A prospective study was conducted in S.M.S Medical College Jaipur, involving 72 singleton fetuses ≥ 28 weeks of gestation divided into two groups: 36 intrauterine growth restricted fetuses (IUGR) and 36 appropriate for gestational age fetuses (AGA). Myocardial performance index was obtained by fetal echocardiography. RESULTS: The mean myocardial performance index in the IUGR fetuses and AGA fetuses was statistically significant and that was 0.62 ± 0.02 and 0.45 ± 0.01, respectively; (p value: < 0.0001). These findings suggest that IUGR induces primary cardiac changes, which could explain the increased predisposition to cardiovascular disease in adult life. This study concluded that Fetal echocardiographic parameters (MPI) identify a high risk group within the IUGR fetuses, which could be targeted for early screening of blood pressure and other cardiovascular risk factors, as well as for promoting a healthy diet and physical exercise.
AIM: Aim of the study is to evaluate the myocardial performance index in intrauterine growth restricted fetuses and compare this index with appropriate for gestational age fetuses. MATERIALS & METHODS: A prospective study was conducted in S.M.S Medical College Jaipur, involving 72 singleton fetuses ≥ 28 weeks of gestation divided into two groups: 36 intrauterine growth restricted fetuses (IUGR) and 36 appropriate for gestational age fetuses (AGA). Myocardial performance index was obtained by fetal echocardiography. RESULTS: The mean myocardial performance index in the IUGR fetuses and AGA fetuses was statistically significant and that was 0.62 ± 0.02 and 0.45 ± 0.01, respectively; (p value: < 0.0001). These findings suggest that IUGR induces primary cardiac changes, which could explain the increased predisposition to cardiovascular disease in adult life. This study concluded that Fetal echocardiographic parameters (MPI) identify a high risk group within the IUGR fetuses, which could be targeted for early screening of blood pressure and other cardiovascular risk factors, as well as for promoting a healthy diet and physical exercise.
Entities:
Keywords:
Fetal echocardiography; Intrauterine growth restricted fetus; Myocardial performance index
Authors: M Pérez-Cruz; M Cruz-Lemini; M T Fernández; J A Parra; J Bartrons; M D Gómez-Roig; F Crispi; E Gratacós Journal: Ultrasound Obstet Gynecol Date: 2015-10 Impact factor: 7.299
Authors: Fatima Crispi; Edgar Hernandez-Andrade; Maurice M A L Pelsers; Walter Plasencia; Jesus Andres Benavides-Serralde; Elisenda Eixarch; Ferdinand Le Noble; Asif Ahmed; Jan F C Glatz; Kypros H Nicolaides; Eduard Gratacos Journal: Am J Obstet Gynecol Date: 2008-09 Impact factor: 8.661