Literature DB >> 3138931

Survival of rough and smooth strains of Brucella abortus in bovine mammary gland macrophages.

B G Harmon1, L G Adams, M Frey.   

Abstract

Chronic bovine brucellosis is characterized by persistent infection of the mammary gland. The interaction of live Brucella abortus with bovine mammary gland macrophages was studied in vitro. Opsonization of smooth B abortus strain 2308 and rough strain 45/20 was required for phagocytosis by mammary gland macrophages. When opsonized with specific antiserum, strains 2308 and 45/20 stimulated a considerable oxidative burst when phagocytized by mammary gland macrophages. Intracellular survival rates for strain 2308 were significantly higher than those for strain 45/20. After being phagocytized, B abortus localized in phagosomes and phagolysosomes of mammary gland macrophages.

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Year:  1988        PMID： 3138931

Source DB:  PubMed          Journal:  Am J Vet Res        ISSN： 0002-9645            Impact factor:   1.156


  34 in total

1.  Interruption of the cydB locus in Brucella abortus attenuates intracellular survival and virulence in the mouse model of infection.

Authors:  S Endley; D McMurray; T A Ficht
Journal:  J Bacteriol       Date:  2001-04       Impact factor: 3.490

2.  Comparative genome analysis of the alpha -proteobacteria: relationships between plant and animal pathogens and host specificity.

Authors:  Renée M Tsolis
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-23       Impact factor: 11.205

3.  Deletion of znuA virulence factor attenuates Brucella abortus and confers protection against wild-type challenge.

Authors:  Xinghong Yang; Todd Becker; Nancy Walters; David W Pascual
Journal:  Infect Immun       Date:  2006-07       Impact factor: 3.441

4.  Discovery of catalases in members of the Chlamydiales order.

Authors:  Brigida Rusconi; Gilbert Greub
Journal:  J Bacteriol       Date:  2013-05-31       Impact factor: 3.490

5.  Ability of mononuclear phagocytes from cattle naturally resistant or susceptible to brucellosis to control in vitro intracellular survival of Brucella abortus.

Authors:  R E Price; J W Templeton; R Smith; L G Adams
Journal:  Infect Immun       Date:  1990-04       Impact factor: 3.441

6.  Immunological response to the Brucella abortus GroEL homolog.

Authors:  J Lin; L G Adams; T A Ficht
Journal:  Infect Immun       Date:  1996-10       Impact factor: 3.441

7.  Intracellular trafficking of Brucella abortus in J774 macrophages.

Authors:  G N Arenas; A S Staskevich; A Aballay; L S Mayorga
Journal:  Infect Immun       Date:  2000-07       Impact factor: 3.441

8.  Brucella abortus rough mutants are cytopathic for macrophages in culture.

Authors:  Jianwu Pei; Thomas A Ficht
Journal:  Infect Immun       Date:  2004-01       Impact factor: 3.441

9.  Immune and pathologic responses in mice infected with Brucella abortus 19, RB51, or 2308.

Authors:  M G Stevens; S C Olsen; G W Pugh; M V Palmer
Journal:  Infect Immun       Date:  1994-08       Impact factor: 3.441

10.  Deletion of purE attenuates Brucella melitensis 16M for growth in human monocyte-derived macrophages.

Authors:  E S Drazek; H S Houng; R M Crawford; T L Hadfield; D L Hoover; R L Warren
Journal:  Infect Immun       Date:  1995-09       Impact factor: 3.441
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