Literature DB >> 313884

[Structure and antipyretic-hypothermizing effect of various pyrazol/1,5-a/pyrimidines].

G Auzzi, L Cecchi, A Costanzo, L Pecori Vettori, F Bruni, R Pirisino, G B Ciottoli.   

Abstract

Structures of condensation products between 3-phenyl-5-aminopyrazole and ethyl ethoxymethylenacetoacetate and ethyl acetonoxalate are demonstrated, namely ethyl 2-phenyl-7-methylpyrazolo[1,5-a]pyrimidin-6-carboxylate and ethyl 2-phenyl-7-methylpyrazolo[1,5-a]pyrimidin-5-carboxylate. Studies on antipyretic and hypothermizing activity of the acid derived from the latter and of other compounds are reported.

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Year:  1979        PMID: 313884

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN: 0430-0920


  1 in total

1.  The reactions of 2-ethoxymethylidene-3-oxo esters and their analogues with 5-aminotetrazole as a way to novel azaheterocycles.

Authors:  Marina V Goryaeva; Yanina V Burgart; Marina A Ezhikova; Mikhail I Kodess; Viktor I Saloutin
Journal:  Beilstein J Org Chem       Date:  2015-03-23       Impact factor: 2.883

  1 in total

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