| Literature DB >> 3138804 |
J G Barr, G M Hogg, E T Smyth.
Abstract
A significant percentage survival, representing a large number of viable cells, can occur in a Staphylococcus aureus population exposed to concentrations of mupirocin up to 1,000 times the minimum inhibitory concentration. An elevated ratio of minimum inhibitory to minimum bactericidal concentration of mupirocin with staphylococci was recorded. Staphylococci which survive exposure to mupirocin may be less sensitive to the subsequent bactericidal action of the antibiotic. The observations may explain the re-colonisation with staphylococci seen in some studies.Entities:
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Year: 1988 PMID： 3138804 PMCID： PMC2448482
Source DB: PubMed Journal: Ulster Med J ISSN： 0041-6193