Literature DB >> 31385960

Brain tumor research in the United Kingdom: current perspective and future challenges. A strategy document from the NCRI Brain Tumor CSG.

Kathreena M Kurian1, Michael D Jenkinson2,3, Paul M Brennan4, Robin Grant4, Sarah Jefferies5, Alasdair G Rooney6, Helen Bulbeck7, Sara C Erridge8, Samantha Mills9, Catherine McBain10, Martin G McCabe11, Stephen J Price12, Silvia Marino13, Erica Moyes14, Wendy Qian15, Adam Waldman16, Babar Vaqas17, Debbie Keatley18, Peter Burchill18, Colin Watts12.   

Abstract

The National Cancer Research Institute (NCRI) is a partnership of charity and government research funders whose purpose is to improve health and quality of life by accelerating progress in cancer-related research through collaboration. Under this umbrella, the NCRI Brain Tumor Clinical Studies Group is focused on improving clinical outcomes for adult patients with brain and central nervous system tumors, including those with brain metastasis from other primary sites. This document discusses the current state of clinical brain tumor research in the United Kingdom and the challenges to increasing study and trial opportunities for patients. The clinical research priorities are defined along with a strategy to strengthen the existing brain tumor research network, improve access to tissue and imaging and to develop the future leadership for brain tumor research in the United Kingdom. This strategy document may serve as a framework for other organizations and countries.

Entities:  

Keywords:  brain tumor; glioma; meningioma; research

Year:  2017        PMID: 31385960      PMCID: PMC6655398          DOI: 10.1093/nop/npx022

Source DB:  PubMed          Journal:  Neurooncol Pract        ISSN: 2054-2577


  13 in total

Review 1.  Symptomatic diagnosis of cancer of the brain and central nervous system in primary care: a systematic review.

Authors:  Mia Schmidt-Hansen; Sabine Berendse; William Hamilton
Journal:  Fam Pract       Date:  2015-10-14       Impact factor: 2.267

Review 2.  The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

Authors:  David N Louis; Arie Perry; Guido Reifenberger; Andreas von Deimling; Dominique Figarella-Branger; Webster K Cavenee; Hiroko Ohgaki; Otmar D Wiestler; Paul Kleihues; David W Ellison
Journal:  Acta Neuropathol       Date:  2016-05-09       Impact factor: 17.088

Review 3.  Management of cerebral metastasis: evidence-based approach for surgery, stereotactic radiosurgery and radiotherapy.

Authors:  Michael D Jenkinson; Brian Haylock; Aditya Shenoy; David Husband; Mohsen Javadpour
Journal:  Eur J Cancer       Date:  2010-12-31       Impact factor: 9.162

Review 4.  Recent developments in chemotherapy for meningiomas: a review.

Authors:  Alan A Moazzam; Naveed Wagle; Gabriel Zada
Journal:  Neurosurg Focus       Date:  2013-12       Impact factor: 4.047

5.  Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.

Authors:  Olivier L Chinot; Wolfgang Wick; Warren Mason; Roger Henriksson; Frank Saran; Ryo Nishikawa; Antoine F Carpentier; Khe Hoang-Xuan; Petr Kavan; Dana Cernea; Alba A Brandes; Magalie Hilton; Lauren Abrey; Timothy Cloughesy
Journal:  N Engl J Med       Date:  2014-02-20       Impact factor: 91.245

6.  Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.

Authors:  Roger Stupp; Warren P Mason; Martin J van den Bent; Michael Weller; Barbara Fisher; Martin J B Taphoorn; Karl Belanger; Alba A Brandes; Christine Marosi; Ulrich Bogdahn; Jürgen Curschmann; Robert C Janzer; Samuel K Ludwin; Thierry Gorlia; Anouk Allgeier; Denis Lacombe; J Gregory Cairncross; Elizabeth Eisenhauer; René O Mirimanoff
Journal:  N Engl J Med       Date:  2005-03-10       Impact factor: 91.245

7.  Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.

Authors:  Roger Stupp; Monika E Hegi; Thierry Gorlia; Sara C Erridge; James Perry; Yong-Kil Hong; Kenneth D Aldape; Benoit Lhermitte; Torsten Pietsch; Danica Grujicic; Joachim Peter Steinbach; Wolfgang Wick; Rafał Tarnawski; Do-Hyun Nam; Peter Hau; Astrid Weyerbrock; Martin J B Taphoorn; Chiung-Chyi Shen; Nalini Rao; László Thurzo; Ulrich Herrlinger; Tejpal Gupta; Rolf-Dieter Kortmann; Krystyna Adamska; Catherine McBain; Alba A Brandes; Joerg Christian Tonn; Oliver Schnell; Thomas Wiegel; Chae-Yong Kim; Louis Burt Nabors; David A Reardon; Martin J van den Bent; Christine Hicking; Andriy Markivskyy; Martin Picard; Michael Weller
Journal:  Lancet Oncol       Date:  2014-08-19       Impact factor: 41.316

8.  Years of life lost (YLL) from cancer is an important measure of population burden--and should be considered when allocating research funds.

Authors:  N G Burnet; S J Jefferies; R J Benson; D P Hunt; F P Treasure
Journal:  Br J Cancer       Date:  2005-01-31       Impact factor: 7.640

Review 9.  The 2007 WHO classification of tumours of the central nervous system.

Authors:  David N Louis; Hiroko Ohgaki; Otmar D Wiestler; Webster K Cavenee; Peter C Burger; Anne Jouvet; Bernd W Scheithauer; Paul Kleihues
Journal:  Acta Neuropathol       Date:  2007-07-06       Impact factor: 17.088

10.  The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial.

Authors:  Michael D Jenkinson; Mohsen Javadpour; Brian J Haylock; Bridget Young; Helen Gillard; Jacqui Vinten; Helen Bulbeck; Kumar Das; Michael Farrell; Seamus Looby; Helen Hickey; Mattheus Preusser; Conor L Mallucci; Dyfrig Hughes; Carrol Gamble; Damien C Weber
Journal:  Trials       Date:  2015-11-14       Impact factor: 2.279

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  4 in total

1.  Hospital teaching status associated with reduced inpatient mortality and perioperative complications in surgical neuro-oncology.

Authors:  Evan M Luther; David McCarthy; Katherine M Berry; Nikhil Rajulapati; Ashish H Shah; Daniel G Eichberg; Ricardo J Komotar; Michael Ivan
Journal:  J Neurooncol       Date:  2020-01-14       Impact factor: 4.130

Review 2.  Fostering open collaboration in drug development for paediatric brain tumours.

Authors:  Jong Fu Wong; Elizabeth J Brown; Eleanor Williams; Alex N Bullock
Journal:  Biochem Soc Trans       Date:  2019-10-31       Impact factor: 5.407

3.  Primary Brain Tumor Research Productivity in Southeast Asia and Its Association With Socioeconomic Determinants and Burden of Disease.

Authors:  Mark Willy L Mondia; Adrian I Espiritu; Roland Dominic G Jamora
Journal:  Front Oncol       Date:  2020-12-23       Impact factor: 6.244

Review 4.  Nanocarriers Call the Last Shot in the Treatment of Brain Cancers.

Authors:  Amin Mehrabian; Mohammad Mashreghi; Saba Dadpour; Ali Badiee; Leila Arabi; Seyedeh Hoda Alavizadeh; Seyedeh Alia Moosavian; Mahmoud Reza Jaafari
Journal:  Technol Cancer Res Treat       Date:  2022 Jan-Dec
  4 in total

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